Gut Microbiome and Common Variable Immunodeficiency: Few Certainties and Many Outstanding Questions

Gut Microbiome and Common Variable Immunodeficiency: Few Certainties and Many Outstanding Questions

Common variable immunodeficiency (CVID) is the most common symptomatic primary antibody immunodeficiency, characterized by reduced serum levels of IgG, IgA, and/or IgM. The vast majority of CVID patients have polygenic inheritance. Immune dysfunction in CVID can frequently involve the gastrointestin...

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Bibliographic Details
Main Authors: Gilda Varricchi, Remo Poto, Gianluca Ianiro, Alessandra Punziano, Gianni Marone, Antonio Gasbarrini, Giuseppe Spadaro
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
common variable immunodeficiency
fecal microbiota transplantation
inflammation
mucosal immunology
microbiota
probiotics
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.712915/full

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