A Rare Case of Primary Breast Osteosarcoma Evaluated with Multiple Modalities
Primary breast osteosarcoma (PBO) is very rare. This report presents a case of POB that was evaluated by multiple modalities. A woman in her 70s presented with a mass of increasing size in her right breast. A mammogram and an ultrasound visualized a lobulated mass containing coarse calcification in...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-06-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/11/7/1170 |
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| author | Tomoyuki Fujioka Mio Mori Iichiroh Onishi Yuka Yashima Emi Yamaga Jun Oyama Kota Yokoyama Kazunori Kubota Goshi Oda Tsuyoshi Nakagawa Ukihide Tateishi |
| author_facet | Tomoyuki Fujioka Mio Mori Iichiroh Onishi Yuka Yashima Emi Yamaga Jun Oyama Kota Yokoyama Kazunori Kubota Goshi Oda Tsuyoshi Nakagawa Ukihide Tateishi |
| author_sort | Tomoyuki Fujioka |
| collection | DOAJ |
| description | Primary breast osteosarcoma (PBO) is very rare. This report presents a case of POB that was evaluated by multiple modalities. A woman in her 70s presented with a mass of increasing size in her right breast. A mammogram and an ultrasound visualized a lobulated mass containing coarse calcification in the right breast. Magnetic resonance imaging showed a strong enhancement effect and high signal on diffusion-weighted imaging. Further imaging on 18F-fluorodeoxyglucose positron-emission tomography and computed tomography exhibited a high uptake. A right total mastectomy was performed. Histologic examination revealed abundant periosteal formation, areas of calcification and moderately pleomorphic oval to spindle-shaped stromal cells, leading to the diagnosis of PBO. The presence of calcified breast tumors exhibiting aggressive growth indicates that PBO should be added to the differential diagnosis. |
| first_indexed | 2024-03-09T04:48:39Z |
| format | Article |
| id | doaj.art-33e1c369788b4e1ba4a42bd7a0cd8590 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-09T04:48:39Z |
| publishDate | 2021-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-33e1c369788b4e1ba4a42bd7a0cd85902023-12-03T13:12:48ZengMDPI AGDiagnostics2075-44182021-06-01117117010.3390/diagnostics11071170A Rare Case of Primary Breast Osteosarcoma Evaluated with Multiple ModalitiesTomoyuki Fujioka0Mio Mori1Iichiroh Onishi2Yuka Yashima3Emi Yamaga4Jun Oyama5Kota Yokoyama6Kazunori Kubota7Goshi Oda8Tsuyoshi Nakagawa9Ukihide Tateishi10Department of Diagnostic Radiology, Tokyo Medical and Dental University, Tokyo 113-8510, JapanDepartment of Diagnostic Radiology, Tokyo Medical and Dental University, Tokyo 113-8510, JapanDepartment of Diagnostic Pathology, Tokyo Medical and Dental University, Tokyo 113-8510, JapanDepartment of Diagnostic Radiology, Tokyo Medical and Dental University, Tokyo 113-8510, JapanDepartment of Diagnostic Radiology, Tokyo Medical and Dental University, Tokyo 113-8510, JapanDepartment of Diagnostic Radiology, Tokyo Medical and Dental University, Tokyo 113-8510, JapanDepartment of Diagnostic Radiology, Tokyo Medical and Dental University, Tokyo 113-8510, JapanDepartment of Radiology, Dokkyo Medical University Saitama Medical Center, Saitama 343-8555, JapanDepartment of Surgery, Breast Surgery, Tokyo Medical and Dental University, Tokyo 113-8510, JapanDepartment of Surgery, Breast Surgery, Tokyo Medical and Dental University, Tokyo 113-8510, JapanDepartment of Diagnostic Radiology, Tokyo Medical and Dental University, Tokyo 113-8510, JapanPrimary breast osteosarcoma (PBO) is very rare. This report presents a case of POB that was evaluated by multiple modalities. A woman in her 70s presented with a mass of increasing size in her right breast. A mammogram and an ultrasound visualized a lobulated mass containing coarse calcification in the right breast. Magnetic resonance imaging showed a strong enhancement effect and high signal on diffusion-weighted imaging. Further imaging on 18F-fluorodeoxyglucose positron-emission tomography and computed tomography exhibited a high uptake. A right total mastectomy was performed. Histologic examination revealed abundant periosteal formation, areas of calcification and moderately pleomorphic oval to spindle-shaped stromal cells, leading to the diagnosis of PBO. The presence of calcified breast tumors exhibiting aggressive growth indicates that PBO should be added to the differential diagnosis.https://www.mdpi.com/2075-4418/11/7/117018F-fluorodeoxyglucose positron-emission tomographymagnetic resonance imagingmammographyprimary breast osteosarcomaultrasound |
| spellingShingle | Tomoyuki Fujioka Mio Mori Iichiroh Onishi Yuka Yashima Emi Yamaga Jun Oyama Kota Yokoyama Kazunori Kubota Goshi Oda Tsuyoshi Nakagawa Ukihide Tateishi A Rare Case of Primary Breast Osteosarcoma Evaluated with Multiple Modalities Diagnostics 18F-fluorodeoxyglucose positron-emission tomography magnetic resonance imaging mammography primary breast osteosarcoma ultrasound |
| title | A Rare Case of Primary Breast Osteosarcoma Evaluated with Multiple Modalities |
| title_full | A Rare Case of Primary Breast Osteosarcoma Evaluated with Multiple Modalities |
| title_fullStr | A Rare Case of Primary Breast Osteosarcoma Evaluated with Multiple Modalities |
| title_full_unstemmed | A Rare Case of Primary Breast Osteosarcoma Evaluated with Multiple Modalities |
| title_short | A Rare Case of Primary Breast Osteosarcoma Evaluated with Multiple Modalities |
| title_sort | rare case of primary breast osteosarcoma evaluated with multiple modalities |
| topic | 18F-fluorodeoxyglucose positron-emission tomography magnetic resonance imaging mammography primary breast osteosarcoma ultrasound |
| url | https://www.mdpi.com/2075-4418/11/7/1170 |
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