Comparison of burrowing and stimuli-evoked pain behaviors as end-points in rat models of inflammatory pain and peripheral neuropathic pain

Comparison of burrowing and stimuli-evoked pain behaviors as end-points in rat models of inflammatory pain and peripheral neuropathic pain

Establishment and validation of ethologically-relevant, non-evoked behavioral end-points as surrogate measures of spontaneous pain in rodent pain models has been proposed as a means to improve preclinical to clinical research translation in the pain field. Here, we compared the utility of burrowing...

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Bibliographic Details
Main Authors: Arjun eMuralidharan, Andy eKuo, Meera eJacob, Jacintha S Lourdesamy, Lara eMelo Sores Pinho De Carvalho, Janet R Nicholson, Laura eCorradini, Maree Therese Smith
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-05-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Inflammatory pain
burrowing
CCI
mechanical allodynia
FCA
Peripheral neuropathic pain
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2016.00088/full

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