Relationship between clockwise rotation of ECG and adverse pregnancy outcome
<b>Objective</b> To observe the incidence of adverse pregnancy outcome in pregnant women with clockwise cardiac rotation indicated by electrocardiogram(ECG) and analyze its clinical significance. <b>Methods</b> A retrospective study was performed on 12 827 pregnant women who...
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| Format: | Article |
| Language: | zho |
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The Editorial Department of Chinese Journal of Clinical Research
2022-12-01
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| Series: | Zhongguo linchuang yanjiu |
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| Online Access: | http://zglcyj.ijournals.cn/ch/reader/view_abstract.aspx?file_no=20221209&flag=1 |
| _version_ | 1828067367041630208 |
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| author | HE Min LYU Li-juan |
| author_facet | HE Min LYU Li-juan |
| author_sort | HE Min |
| collection | DOAJ |
| description | <b>Objective</b> To observe the incidence of adverse pregnancy outcome in pregnant women with clockwise cardiac rotation indicated by electrocardiogram(ECG) and analyze its clinical significance. <b>Methods</b> A retrospective study was performed on 12 827 pregnant women who were admitted to Guangdong Province Maternity and Child Health Hospital for ECG examination from January 1st, 2016 to December 31st, 2018(from card establishment to 27<sup>+</sup>6 weeks of gestation). The participants were dichotomized two groups according to the presence and absence of clockwise rotation in ECG. The associations of clockwise rotation with stillbirth, preeclampsia and thrombotic disease were analyzed. The significant covariates(including age, body mass index, gravidity, parity, gestational hypertension, multiple pregnancy, gestational diabetes mellitus and pregestational diabetes mellitus) using univariate analysis were adjusted by multivariate logistic analysis. <b>Results</b> Out of the pregnant women in middle and early pregnancy, there were 134 pregnant women with clockwise cardiac rotation and 12 693 pregnant women without cardiac transposition. The incidence of thrombotic disease in patients with clockwise rotation was significantly higher than that in patients without clockwise rotation ［2.24%(3/134) <i>vs</i> 0.07%(9/12 693), <i>P</i>＜0.01］. After multivariable adjustment, the risk of thrombotic disease in pregnant women with clockwise rotation remained significantly higher(<i>OR</i>=28.824, 95%<i>CI</i>: 7.248-114.618, <i>P</i>＜0.01). <b>Conclusion</b> Although the prevalence of ECG-indicated clockwise rotation is low among pregnant women during pregnancy, it may be related to thrombotic disease, suggesting that further screening should be conducted for the related risks of thrombotic disease.
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| first_indexed | 2024-04-10T23:44:31Z |
| format | Article |
| id | doaj.art-33e72fc8501141418c754a3fae932739 |
| institution | Directory Open Access Journal |
| issn | 1674-8182 |
| language | zho |
| last_indexed | 2024-04-10T23:44:31Z |
| publishDate | 2022-12-01 |
| publisher | The Editorial Department of Chinese Journal of Clinical Research |
| record_format | Article |
| series | Zhongguo linchuang yanjiu |
| spelling | doaj.art-33e72fc8501141418c754a3fae9327392023-01-11T04:59:56ZzhoThe Editorial Department of Chinese Journal of Clinical ResearchZhongguo linchuang yanjiu1674-81822022-12-0135121676167910.13429/j.cnki.cjcr.2022.12.009Relationship between clockwise rotation of ECG and adverse pregnancy outcomeHE Min0LYU Li-juan1Functional Department, Ezhou Central Hospital, Ezhou, Hubei 436000, ChinaPrenatal Diagnosis Center of Guangdong Maternal and Child Health Hospital, Guangzhou, Guangdong 510000, China<b>Objective</b> To observe the incidence of adverse pregnancy outcome in pregnant women with clockwise cardiac rotation indicated by electrocardiogram(ECG) and analyze its clinical significance. <b>Methods</b> A retrospective study was performed on 12 827 pregnant women who were admitted to Guangdong Province Maternity and Child Health Hospital for ECG examination from January 1st, 2016 to December 31st, 2018(from card establishment to 27<sup>+</sup>6 weeks of gestation). The participants were dichotomized two groups according to the presence and absence of clockwise rotation in ECG. The associations of clockwise rotation with stillbirth, preeclampsia and thrombotic disease were analyzed. The significant covariates(including age, body mass index, gravidity, parity, gestational hypertension, multiple pregnancy, gestational diabetes mellitus and pregestational diabetes mellitus) using univariate analysis were adjusted by multivariate logistic analysis. <b>Results</b> Out of the pregnant women in middle and early pregnancy, there were 134 pregnant women with clockwise cardiac rotation and 12 693 pregnant women without cardiac transposition. The incidence of thrombotic disease in patients with clockwise rotation was significantly higher than that in patients without clockwise rotation ［2.24%(3/134) <i>vs</i> 0.07%(9/12 693), <i>P</i>＜0.01］. After multivariable adjustment, the risk of thrombotic disease in pregnant women with clockwise rotation remained significantly higher(<i>OR</i>=28.824, 95%<i>CI</i>: 7.248-114.618, <i>P</i>＜0.01). <b>Conclusion</b> Although the prevalence of ECG-indicated clockwise rotation is low among pregnant women during pregnancy, it may be related to thrombotic disease, suggesting that further screening should be conducted for the related risks of thrombotic disease. http://zglcyj.ijournals.cn/ch/reader/view_abstract.aspx?file_no=20221209&flag=1pregnancyelectrocardiographyclockwise rotationpregnant outcomethrombotic diseasepreeclampsiastillbirth |
| spellingShingle | HE Min LYU Li-juan Relationship between clockwise rotation of ECG and adverse pregnancy outcome Zhongguo linchuang yanjiu pregnancy electrocardiography clockwise rotation pregnant outcome thrombotic disease preeclampsia stillbirth |
| title | Relationship between clockwise rotation of ECG and adverse pregnancy outcome |
| title_full | Relationship between clockwise rotation of ECG and adverse pregnancy outcome |
| title_fullStr | Relationship between clockwise rotation of ECG and adverse pregnancy outcome |
| title_full_unstemmed | Relationship between clockwise rotation of ECG and adverse pregnancy outcome |
| title_short | Relationship between clockwise rotation of ECG and adverse pregnancy outcome |
| title_sort | relationship between clockwise rotation of ecg and adverse pregnancy outcome |
| topic | pregnancy electrocardiography clockwise rotation pregnant outcome thrombotic disease preeclampsia stillbirth |
| url | http://zglcyj.ijournals.cn/ch/reader/view_abstract.aspx?file_no=20221209&flag=1 |
| work_keys_str_mv | AT hemin relationshipbetweenclockwiserotationofecgandadversepregnancyoutcome AT lyulijuan relationshipbetweenclockwiserotationofecgandadversepregnancyoutcome |