Status of insecticide susceptibility in <it>Anopheles arabiensis </it>from Mwea rice irrigation scheme, Central Kenya
<p>Abstract</p> <p>Background</p> <p>Control of the Anopheline mosquito vectors of malaria by use of insecticides has been shown to impact on both morbidity and mortality due to this disease. Evidence of insecticide resistance in different settings necessitates surveill...
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| Format: | Article |
| Language: | English |
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BMC
2006-06-01
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| Series: | Malaria Journal |
| Online Access: | http://www.malariajournal.com/content/5/1/46 |
| _version_ | 1831568193699708928 |
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| author | Vulule John M Kamau Luna |
| author_facet | Vulule John M Kamau Luna |
| author_sort | Vulule John M |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Control of the Anopheline mosquito vectors of malaria by use of insecticides has been shown to impact on both morbidity and mortality due to this disease. Evidence of insecticide resistance in different settings necessitates surveillance studies to allow prompt detection of resistance should it arise and thus enable its management. Possible resistance by <it>Anopheles arabiensis </it>mosquitoes from Mwea rice irrigation scheme in Central Kenya to insecticides in the four classes of insecticides approved by WHO for indoor residual spraying was investigated.</p> <p>Methods</p> <p>Susceptibility to DDT (an organochlorine), fenitrothion (an organophosphate), bendiocarb (a carbamate), lambdacyhalothrin and permethrin (both pyrethroids) was tested using standard WHO diagnostic bioassay kits. Bioassays were performed on non-blood fed mosquitoes one- to three-day old. Knockdown was recorded every 10 min and mortality 24 h post-exposure was noted.</p> <p>Results</p> <p>Mortality 24 h post-exposure was 100% for all insecticides except for lambdacyhalothrin, which averaged 99.46%. Knockdown rates at 10 min intervals were not significantly different between the Mwea population and the susceptible KISUMU strain of <it>Anopheles gambiae </it>sensu stricto control. The KDT<sub>50 </sub>and KDT<sub>95 </sub>values for the Mwea population were either lower than those for the control or higher by factors of no more than 2 for most comparisons and compared well with those of <it>An. gambiae </it>sensu lato categorized as susceptible in other studies.</p> <p>Conclusion</p> <p>These results suggest that the Mwea population of <it>An. arabiensis </it>is susceptible to all the insecticides tested. This implies that vector control measures employing any of these insecticides would not be hampered by resistance.</p> |
| first_indexed | 2024-12-17T12:11:36Z |
| format | Article |
| id | doaj.art-33f5228707424b4783ac074522c42291 |
| institution | Directory Open Access Journal |
| issn | 1475-2875 |
| language | English |
| last_indexed | 2024-12-17T12:11:36Z |
| publishDate | 2006-06-01 |
| publisher | BMC |
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| series | Malaria Journal |
| spelling | doaj.art-33f5228707424b4783ac074522c422912022-12-21T21:49:23ZengBMCMalaria Journal1475-28752006-06-01514610.1186/1475-2875-5-46Status of insecticide susceptibility in <it>Anopheles arabiensis </it>from Mwea rice irrigation scheme, Central KenyaVulule John MKamau Luna<p>Abstract</p> <p>Background</p> <p>Control of the Anopheline mosquito vectors of malaria by use of insecticides has been shown to impact on both morbidity and mortality due to this disease. Evidence of insecticide resistance in different settings necessitates surveillance studies to allow prompt detection of resistance should it arise and thus enable its management. Possible resistance by <it>Anopheles arabiensis </it>mosquitoes from Mwea rice irrigation scheme in Central Kenya to insecticides in the four classes of insecticides approved by WHO for indoor residual spraying was investigated.</p> <p>Methods</p> <p>Susceptibility to DDT (an organochlorine), fenitrothion (an organophosphate), bendiocarb (a carbamate), lambdacyhalothrin and permethrin (both pyrethroids) was tested using standard WHO diagnostic bioassay kits. Bioassays were performed on non-blood fed mosquitoes one- to three-day old. Knockdown was recorded every 10 min and mortality 24 h post-exposure was noted.</p> <p>Results</p> <p>Mortality 24 h post-exposure was 100% for all insecticides except for lambdacyhalothrin, which averaged 99.46%. Knockdown rates at 10 min intervals were not significantly different between the Mwea population and the susceptible KISUMU strain of <it>Anopheles gambiae </it>sensu stricto control. The KDT<sub>50 </sub>and KDT<sub>95 </sub>values for the Mwea population were either lower than those for the control or higher by factors of no more than 2 for most comparisons and compared well with those of <it>An. gambiae </it>sensu lato categorized as susceptible in other studies.</p> <p>Conclusion</p> <p>These results suggest that the Mwea population of <it>An. arabiensis </it>is susceptible to all the insecticides tested. This implies that vector control measures employing any of these insecticides would not be hampered by resistance.</p>http://www.malariajournal.com/content/5/1/46 |
| spellingShingle | Vulule John M Kamau Luna Status of insecticide susceptibility in <it>Anopheles arabiensis </it>from Mwea rice irrigation scheme, Central Kenya Malaria Journal |
| title | Status of insecticide susceptibility in <it>Anopheles arabiensis </it>from Mwea rice irrigation scheme, Central Kenya |
| title_full | Status of insecticide susceptibility in <it>Anopheles arabiensis </it>from Mwea rice irrigation scheme, Central Kenya |
| title_fullStr | Status of insecticide susceptibility in <it>Anopheles arabiensis </it>from Mwea rice irrigation scheme, Central Kenya |
| title_full_unstemmed | Status of insecticide susceptibility in <it>Anopheles arabiensis </it>from Mwea rice irrigation scheme, Central Kenya |
| title_short | Status of insecticide susceptibility in <it>Anopheles arabiensis </it>from Mwea rice irrigation scheme, Central Kenya |
| title_sort | status of insecticide susceptibility in it anopheles arabiensis it from mwea rice irrigation scheme central kenya |
| url | http://www.malariajournal.com/content/5/1/46 |
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