ROLE OF PERIVASCULAR ADIPOSE TISSUE IN THE DEVELOPMENT OF ATHEROSCLEROTIC AND NONATHEROSCLEROTIC DISEASES
Perivascular adipose tissue surrounds most large blood vessels and plays an important role in vascular homeostasis. Recent studies have shown that perivascular adipose tissue effects vasodilation and vasoconstriction, which indicates that the perivascular adipose tissue regulates tone and diameter o...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
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St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
2019-10-01
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| Series: | Медицинская иммунология |
| Subjects: | |
| Online Access: | https://www.mimmun.ru/mimmun/article/view/1607 |
| _version_ | 1797197936657956864 |
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| author | E. G. Uchasova O V Gruzdeva Yu A Dyleva E V Belik |
| author_facet | E. G. Uchasova O V Gruzdeva Yu A Dyleva E V Belik |
| author_sort | E. G. Uchasova |
| collection | DOAJ |
| description | Perivascular adipose tissue surrounds most large blood vessels and plays an important role in vascular homeostasis. Recent studies have shown that perivascular adipose tissue effects vasodilation and vasoconstriction, which indicates that the perivascular adipose tissue regulates tone and diameter of the vessels. Adipocytokines and chemokines, secreted from the perivascular adipose tissue, apparently have direct access to the adjacent arterial wall by diffusion, or through vasa vasorum. The present data indicate that perivascular adipose tissue plays an important role in atherosclerosis, hypertension. Recently, some studies were performed that examined the role of perivascular adipose tissue in non-atherosclerotic vascular diseases, such as neointimal formation, aortic aneurysm, arterial stiffness and vasculitis. The present review will discuss a role of perivascular adipose tissue in pathogenesis of atherosclerosis, hypertension and non-atherosclerotic vascular diseases. |
| first_indexed | 2024-03-08T05:48:31Z |
| format | Article |
| id | doaj.art-33f6650dffd545e9b3251fe59ba4493a |
| institution | Directory Open Access Journal |
| issn | 1563-0625 2313-741X |
| language | Russian |
| last_indexed | 2024-04-24T06:51:53Z |
| publishDate | 2019-10-01 |
| publisher | St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists |
| record_format | Article |
| series | Медицинская иммунология |
| spelling | doaj.art-33f6650dffd545e9b3251fe59ba4493a2024-04-22T13:07:43ZrusSt. Petersburg branch of the Russian Association of Allergologists and Clinical ImmunologistsМедицинская иммунология1563-06252313-741X2019-10-0121463364210.15789/1563-0625-2019-4-633-6421129ROLE OF PERIVASCULAR ADIPOSE TISSUE IN THE DEVELOPMENT OF ATHEROSCLEROTIC AND NONATHEROSCLEROTIC DISEASESE. G. Uchasova0O V Gruzdeva1Yu A Dyleva2E V Belik3Federal State Research Institute for Complex Issues of Cardiovascular DiseasesFederal State Research Institute for Complex Issues of Cardiovascular Diseases; Kemerovo State Medical UniversityFederal State Research Institute for Complex Issues of Cardiovascular DiseasesFederal State Research Institute for Complex Issues of Cardiovascular DiseasesPerivascular adipose tissue surrounds most large blood vessels and plays an important role in vascular homeostasis. Recent studies have shown that perivascular adipose tissue effects vasodilation and vasoconstriction, which indicates that the perivascular adipose tissue regulates tone and diameter of the vessels. Adipocytokines and chemokines, secreted from the perivascular adipose tissue, apparently have direct access to the adjacent arterial wall by diffusion, or through vasa vasorum. The present data indicate that perivascular adipose tissue plays an important role in atherosclerosis, hypertension. Recently, some studies were performed that examined the role of perivascular adipose tissue in non-atherosclerotic vascular diseases, such as neointimal formation, aortic aneurysm, arterial stiffness and vasculitis. The present review will discuss a role of perivascular adipose tissue in pathogenesis of atherosclerosis, hypertension and non-atherosclerotic vascular diseases.https://www.mimmun.ru/mimmun/article/view/1607perivascular adipose tissueadipokinescytokinesatherosclerosishypertensioncardiovascular diseases |
| spellingShingle | E. G. Uchasova O V Gruzdeva Yu A Dyleva E V Belik ROLE OF PERIVASCULAR ADIPOSE TISSUE IN THE DEVELOPMENT OF ATHEROSCLEROTIC AND NONATHEROSCLEROTIC DISEASES Медицинская иммунология perivascular adipose tissue adipokines cytokines atherosclerosis hypertension cardiovascular diseases |
| title | ROLE OF PERIVASCULAR ADIPOSE TISSUE IN THE DEVELOPMENT OF ATHEROSCLEROTIC AND NONATHEROSCLEROTIC DISEASES |
| title_full | ROLE OF PERIVASCULAR ADIPOSE TISSUE IN THE DEVELOPMENT OF ATHEROSCLEROTIC AND NONATHEROSCLEROTIC DISEASES |
| title_fullStr | ROLE OF PERIVASCULAR ADIPOSE TISSUE IN THE DEVELOPMENT OF ATHEROSCLEROTIC AND NONATHEROSCLEROTIC DISEASES |
| title_full_unstemmed | ROLE OF PERIVASCULAR ADIPOSE TISSUE IN THE DEVELOPMENT OF ATHEROSCLEROTIC AND NONATHEROSCLEROTIC DISEASES |
| title_short | ROLE OF PERIVASCULAR ADIPOSE TISSUE IN THE DEVELOPMENT OF ATHEROSCLEROTIC AND NONATHEROSCLEROTIC DISEASES |
| title_sort | role of perivascular adipose tissue in the development of atherosclerotic and nonatherosclerotic diseases |
| topic | perivascular adipose tissue adipokines cytokines atherosclerosis hypertension cardiovascular diseases |
| url | https://www.mimmun.ru/mimmun/article/view/1607 |
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