Uric acid levels are associated with severity and mortality in patients with acute coronary syndrome
Acute coronary syndrome (ACS) causes a serious of coronary artery diseases that associated with sudden and reduced blood flow to the heart. The aim of this study was to assess the potential of serum uric acid (SUA) to predict severity and mortality in patients with ACS. According to their SUA level...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Innovation Publishing House Pte. Ltd.
2022-07-01
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| Series: | STEMedicine |
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| Online Access: | https://stemedicine.org/index.php/stem/article/view/131 |
| _version_ | 1818470637056819200 |
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| author | Hui Feng Huaping Pan Wei Yao |
| author_facet | Hui Feng Huaping Pan Wei Yao |
| author_sort | Hui Feng |
| collection | DOAJ |
| description |
Acute coronary syndrome (ACS) causes a serious of coronary artery diseases that associated with sudden and reduced blood flow to the heart. The aim of this study was to assess the potential of serum uric acid (SUA) to predict severity and mortality in patients with ACS. According to their SUA levels, eligible participants were assigned into the Hyperuricemia group and the Normouricemia group (control group). All the patients were requested to enroll into a 1-year follow-up, and the final clinical outcomes included the SYNTAX and Gensini scores, major adverse cardiovascular events (MACEs), and cardiovascular mortality. In total, 874 participants were followed-up. Individuals with high levels of uric acid bore more disease vessels exhibited higher SYNTAX and Gensini scores. Besides, patients in the Hyperuricemia group showed elevated rates of MACE and cardiovascular mortality. High SUA level is positively associated with severity and mortality of patients with ACS. SUA might be a novel ACS prediction marker and risk factor in clinical diagnosis.
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| first_indexed | 2024-04-13T21:40:30Z |
| format | Article |
| id | doaj.art-33f75c05483044188076dd9a70d9c1ab |
| institution | Directory Open Access Journal |
| issn | 2705-1188 |
| language | English |
| last_indexed | 2024-04-13T21:40:30Z |
| publishDate | 2022-07-01 |
| publisher | Innovation Publishing House Pte. Ltd. |
| record_format | Article |
| series | STEMedicine |
| spelling | doaj.art-33f75c05483044188076dd9a70d9c1ab2022-12-22T02:28:47ZengInnovation Publishing House Pte. Ltd.STEMedicine2705-11882022-07-013310.37175/stemedicine.v3i3.131Uric acid levels are associated with severity and mortality in patients with acute coronary syndromeHui Feng0Huaping Pan1Wei Yao2Department of Rehabilitation Medicine, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, ChinaDepartment of Rehabilitation Medicine, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, ChinaDepartment of Rehabilitation Medicine, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, China Acute coronary syndrome (ACS) causes a serious of coronary artery diseases that associated with sudden and reduced blood flow to the heart. The aim of this study was to assess the potential of serum uric acid (SUA) to predict severity and mortality in patients with ACS. According to their SUA levels, eligible participants were assigned into the Hyperuricemia group and the Normouricemia group (control group). All the patients were requested to enroll into a 1-year follow-up, and the final clinical outcomes included the SYNTAX and Gensini scores, major adverse cardiovascular events (MACEs), and cardiovascular mortality. In total, 874 participants were followed-up. Individuals with high levels of uric acid bore more disease vessels exhibited higher SYNTAX and Gensini scores. Besides, patients in the Hyperuricemia group showed elevated rates of MACE and cardiovascular mortality. High SUA level is positively associated with severity and mortality of patients with ACS. SUA might be a novel ACS prediction marker and risk factor in clinical diagnosis. https://stemedicine.org/index.php/stem/article/view/131uric acidacute coronary syndromesprediction markerrisk factor |
| spellingShingle | Hui Feng Huaping Pan Wei Yao Uric acid levels are associated with severity and mortality in patients with acute coronary syndrome STEMedicine uric acid acute coronary syndromes prediction marker risk factor |
| title | Uric acid levels are associated with severity and mortality in patients with acute coronary syndrome |
| title_full | Uric acid levels are associated with severity and mortality in patients with acute coronary syndrome |
| title_fullStr | Uric acid levels are associated with severity and mortality in patients with acute coronary syndrome |
| title_full_unstemmed | Uric acid levels are associated with severity and mortality in patients with acute coronary syndrome |
| title_short | Uric acid levels are associated with severity and mortality in patients with acute coronary syndrome |
| title_sort | uric acid levels are associated with severity and mortality in patients with acute coronary syndrome |
| topic | uric acid acute coronary syndromes prediction marker risk factor |
| url | https://stemedicine.org/index.php/stem/article/view/131 |
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