Spermine protects intestinal barrier integrity through ras-related C3 botulinum toxin substrate 1/phospholipase C-γ1 signaling pathway in piglets

Spermine protects intestinal barrier integrity through ras-related C3 botulinum toxin substrate 1/phospholipase C-γ1 signaling pathway in piglets

Weaning stress can cause tight junctions damage and intestinal permeability enhancement, which leads to intestinal imbalance and growth retardation, thereby causing damage to piglet growth and development. Spermine can reduce stress. However, the mechanism of spermine modulating the intestinal integ...

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Bibliographic Details
Main Authors: Guangmang Liu, Xiaomei Xu, Caimei Wu, Gang Jia, Hua Zhao, Xiaoling Chen, Gang Tian, Jingyi Cai, Jing Wang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-03-01
Series:Animal Nutrition
Subjects:
Spermine
Intestinal barrier
Rac1/PLC-γ1 signaling pathway
Intestinal integrity
Online Access:http://www.sciencedirect.com/science/article/pii/S240565452100175X

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