Outcomes of chronic total occlusion percutaneous coronary intervention from the RAIAN (RAjaie - Iran) registry
Objective: While most of the evidence in CTO interventions emerge from Western and Japanese studies, few data have been published up today from the Middle East. Objective of this study was to evaluate technical success rates and clinical outcomes of an Iranian population undergoing CTO PCI in a tert...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-11-01
|
| Series: | Indian Heart Journal |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0019483223001669 |
| _version_ | 1797388866995355648 |
|---|---|
| author | Bahram Mohebbi Parham Sadeghipour Reza Zolfaghari Giuseppe Vadalà Ehsan Khalilipur Ali Zahedmehr Davide Diana Mohsen Maadani Farshad Shakerian Reza Kiani Zahara Hosseini Alireza Rashidinejad Mostafa Rouzitalab Somayeh Khalesi Vahid Toulabi Vincenzo Sucato Luca Di Fazio Maisam Taherian Saeed Amiripouya Shahrzad Ashuri Ayatollah Bayatian Sajad Naderi Hooman Bakhshandeh Jamal Moosavi Seifollah Abdi Ata Firouzi Mohammad Javad Alemzadeh-Ansari Alfredo R. Galassi |
| author_facet | Bahram Mohebbi Parham Sadeghipour Reza Zolfaghari Giuseppe Vadalà Ehsan Khalilipur Ali Zahedmehr Davide Diana Mohsen Maadani Farshad Shakerian Reza Kiani Zahara Hosseini Alireza Rashidinejad Mostafa Rouzitalab Somayeh Khalesi Vahid Toulabi Vincenzo Sucato Luca Di Fazio Maisam Taherian Saeed Amiripouya Shahrzad Ashuri Ayatollah Bayatian Sajad Naderi Hooman Bakhshandeh Jamal Moosavi Seifollah Abdi Ata Firouzi Mohammad Javad Alemzadeh-Ansari Alfredo R. Galassi |
| author_sort | Bahram Mohebbi |
| collection | DOAJ |
| description | Objective: While most of the evidence in CTO interventions emerge from Western and Japanese studies, few data have been published up today from the Middle East. Objective of this study was to evaluate technical success rates and clinical outcomes of an Iranian population undergoing CTO PCI in a tertiary referral hospital. Moreover, we sought to evaluate the efficacy of our CTO teaching program. Methods: This is a retrospective single-center cohort study including 790 patients who underwent CTO PCI performed by operators with different volumes of CTOs PCI performed per year. According to PCI result, all patients have been divided into successful (n = 555, 70.3 %) and unsuccessful (n = 235, 29.7 %) groups. Study endpoints were Major Adverse Cardiovascular Events and Health Status Improvement evaluated using the Seattle Angina Questionnaire at one year. Results: A global success rate of 70 % for antegrade and 80 % for retrograde approach was shown despite the lack of some CTO-dedicated devices. During the enrollment period, the success rate increased significantly among operators with a lower number of CTO procedures per year. One-year MACE rate was similar in both successful and unsuccessful groups (13.5 % in successful and 10.6 % in unsuccessful group, p = 0.173). One year patients’ health status improved significantly only in successful group. Conclusions: No significant differences of in-hospital and one-year MACE were found between the successful and unsuccessful groups. Angina symptoms and quality of life significantly improved after successful CTO PCI. The RAIAN registry confirmed the importance of operator expertise for CTO PCI success. |
| first_indexed | 2024-03-08T22:47:21Z |
| format | Article |
| id | doaj.art-33fc90fba6a9491b8135f9eef38c0d59 |
| institution | Directory Open Access Journal |
| issn | 0019-4832 |
| language | English |
| last_indexed | 2024-03-08T22:47:21Z |
| publishDate | 2023-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Indian Heart Journal |
| spelling | doaj.art-33fc90fba6a9491b8135f9eef38c0d592023-12-17T06:37:07ZengElsevierIndian Heart Journal0019-48322023-11-01756429435Outcomes of chronic total occlusion percutaneous coronary intervention from the RAIAN (RAjaie - Iran) registryBahram Mohebbi0Parham Sadeghipour1Reza Zolfaghari2Giuseppe Vadalà3Ehsan Khalilipur4Ali Zahedmehr5Davide Diana6Mohsen Maadani7Farshad Shakerian8Reza Kiani9Zahara Hosseini10Alireza Rashidinejad11Mostafa Rouzitalab12Somayeh Khalesi13Vahid Toulabi14Vincenzo Sucato15Luca Di Fazio16Maisam Taherian17Saeed Amiripouya18Shahrzad Ashuri19Ayatollah Bayatian20Sajad Naderi21Hooman Bakhshandeh22Jamal Moosavi23Seifollah Abdi24Ata Firouzi25Mohammad Javad Alemzadeh-Ansari26Alfredo R. Galassi27Cardiovascular Intervention Research Center, Cardio-Oncology Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IranCardiovascular Intervention Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IranCardiovascular Intervention Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IranCardiology Unit, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (ProMISE) “G. D'Alessandro”, Paolo Giaccone Hospital, University of Palermo, Italy; Corresponding author. Cardiology Unit, University Hospital “P. Giaccone” Via Del Vespro 121, 90127, Palermo, Italy.Cardiovascular Intervention Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IranCardiovascular Intervention Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IranDepartment of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (ProMISE), University of Palermo, Palermo, ItalyCardiovascular Intervention Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IranCardiovascular Intervention Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IranCardiovascular Intervention Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IranCardiovascular Intervention Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IranCardiovascular Intervention Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IranDepartment of Cardiology, Sina Hospital, Tehran University of Medical Sciences, Tehran, IranCardiovascular Intervention Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IranCardiovascular Intervention Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IranCardiology Unit, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (ProMISE) “G. D'Alessandro”, Paolo Giaccone Hospital, University of Palermo, ItalyCardiology Unit, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (ProMISE) “G. D'Alessandro”, Paolo Giaccone Hospital, University of Palermo, ItalyCardiovascular Intervention Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IranCardiovascular Intervention Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IranCardiovascular Intervention Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IranCardiovascular Intervention Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IranCardiovascular Intervention Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IranCardiovascular Intervention Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IranCardiovascular Intervention Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IranCardiovascular Intervention Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IranCardiovascular Intervention Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IranCardiovascular Intervention Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IranDepartment of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (ProMISE), University of Palermo, Palermo, ItalyObjective: While most of the evidence in CTO interventions emerge from Western and Japanese studies, few data have been published up today from the Middle East. Objective of this study was to evaluate technical success rates and clinical outcomes of an Iranian population undergoing CTO PCI in a tertiary referral hospital. Moreover, we sought to evaluate the efficacy of our CTO teaching program. Methods: This is a retrospective single-center cohort study including 790 patients who underwent CTO PCI performed by operators with different volumes of CTOs PCI performed per year. According to PCI result, all patients have been divided into successful (n = 555, 70.3 %) and unsuccessful (n = 235, 29.7 %) groups. Study endpoints were Major Adverse Cardiovascular Events and Health Status Improvement evaluated using the Seattle Angina Questionnaire at one year. Results: A global success rate of 70 % for antegrade and 80 % for retrograde approach was shown despite the lack of some CTO-dedicated devices. During the enrollment period, the success rate increased significantly among operators with a lower number of CTO procedures per year. One-year MACE rate was similar in both successful and unsuccessful groups (13.5 % in successful and 10.6 % in unsuccessful group, p = 0.173). One year patients’ health status improved significantly only in successful group. Conclusions: No significant differences of in-hospital and one-year MACE were found between the successful and unsuccessful groups. Angina symptoms and quality of life significantly improved after successful CTO PCI. The RAIAN registry confirmed the importance of operator expertise for CTO PCI success.http://www.sciencedirect.com/science/article/pii/S0019483223001669Chronic total occlusion (CTO)Percutaneous coronary intervention (PCI)Quality of life (QoL)Chronic coronary artery disease (CCAD) |
| spellingShingle | Bahram Mohebbi Parham Sadeghipour Reza Zolfaghari Giuseppe Vadalà Ehsan Khalilipur Ali Zahedmehr Davide Diana Mohsen Maadani Farshad Shakerian Reza Kiani Zahara Hosseini Alireza Rashidinejad Mostafa Rouzitalab Somayeh Khalesi Vahid Toulabi Vincenzo Sucato Luca Di Fazio Maisam Taherian Saeed Amiripouya Shahrzad Ashuri Ayatollah Bayatian Sajad Naderi Hooman Bakhshandeh Jamal Moosavi Seifollah Abdi Ata Firouzi Mohammad Javad Alemzadeh-Ansari Alfredo R. Galassi Outcomes of chronic total occlusion percutaneous coronary intervention from the RAIAN (RAjaie - Iran) registry Indian Heart Journal Chronic total occlusion (CTO) Percutaneous coronary intervention (PCI) Quality of life (QoL) Chronic coronary artery disease (CCAD) |
| title | Outcomes of chronic total occlusion percutaneous coronary intervention from the RAIAN (RAjaie - Iran) registry |
| title_full | Outcomes of chronic total occlusion percutaneous coronary intervention from the RAIAN (RAjaie - Iran) registry |
| title_fullStr | Outcomes of chronic total occlusion percutaneous coronary intervention from the RAIAN (RAjaie - Iran) registry |
| title_full_unstemmed | Outcomes of chronic total occlusion percutaneous coronary intervention from the RAIAN (RAjaie - Iran) registry |
| title_short | Outcomes of chronic total occlusion percutaneous coronary intervention from the RAIAN (RAjaie - Iran) registry |
| title_sort | outcomes of chronic total occlusion percutaneous coronary intervention from the raian rajaie iran registry |
| topic | Chronic total occlusion (CTO) Percutaneous coronary intervention (PCI) Quality of life (QoL) Chronic coronary artery disease (CCAD) |
| url | http://www.sciencedirect.com/science/article/pii/S0019483223001669 |
| work_keys_str_mv | AT bahrammohebbi outcomesofchronictotalocclusionpercutaneouscoronaryinterventionfromtheraianrajaieiranregistry AT parhamsadeghipour outcomesofchronictotalocclusionpercutaneouscoronaryinterventionfromtheraianrajaieiranregistry AT rezazolfaghari outcomesofchronictotalocclusionpercutaneouscoronaryinterventionfromtheraianrajaieiranregistry AT giuseppevadala outcomesofchronictotalocclusionpercutaneouscoronaryinterventionfromtheraianrajaieiranregistry AT ehsankhalilipur outcomesofchronictotalocclusionpercutaneouscoronaryinterventionfromtheraianrajaieiranregistry AT alizahedmehr outcomesofchronictotalocclusionpercutaneouscoronaryinterventionfromtheraianrajaieiranregistry AT davidediana outcomesofchronictotalocclusionpercutaneouscoronaryinterventionfromtheraianrajaieiranregistry AT mohsenmaadani outcomesofchronictotalocclusionpercutaneouscoronaryinterventionfromtheraianrajaieiranregistry AT farshadshakerian outcomesofchronictotalocclusionpercutaneouscoronaryinterventionfromtheraianrajaieiranregistry AT rezakiani outcomesofchronictotalocclusionpercutaneouscoronaryinterventionfromtheraianrajaieiranregistry AT zaharahosseini outcomesofchronictotalocclusionpercutaneouscoronaryinterventionfromtheraianrajaieiranregistry AT alirezarashidinejad outcomesofchronictotalocclusionpercutaneouscoronaryinterventionfromtheraianrajaieiranregistry AT mostafarouzitalab outcomesofchronictotalocclusionpercutaneouscoronaryinterventionfromtheraianrajaieiranregistry AT somayehkhalesi outcomesofchronictotalocclusionpercutaneouscoronaryinterventionfromtheraianrajaieiranregistry AT vahidtoulabi outcomesofchronictotalocclusionpercutaneouscoronaryinterventionfromtheraianrajaieiranregistry AT vincenzosucato outcomesofchronictotalocclusionpercutaneouscoronaryinterventionfromtheraianrajaieiranregistry AT lucadifazio outcomesofchronictotalocclusionpercutaneouscoronaryinterventionfromtheraianrajaieiranregistry AT maisamtaherian outcomesofchronictotalocclusionpercutaneouscoronaryinterventionfromtheraianrajaieiranregistry AT saeedamiripouya outcomesofchronictotalocclusionpercutaneouscoronaryinterventionfromtheraianrajaieiranregistry AT shahrzadashuri outcomesofchronictotalocclusionpercutaneouscoronaryinterventionfromtheraianrajaieiranregistry AT ayatollahbayatian outcomesofchronictotalocclusionpercutaneouscoronaryinterventionfromtheraianrajaieiranregistry AT sajadnaderi outcomesofchronictotalocclusionpercutaneouscoronaryinterventionfromtheraianrajaieiranregistry AT hoomanbakhshandeh outcomesofchronictotalocclusionpercutaneouscoronaryinterventionfromtheraianrajaieiranregistry AT jamalmoosavi outcomesofchronictotalocclusionpercutaneouscoronaryinterventionfromtheraianrajaieiranregistry AT seifollahabdi outcomesofchronictotalocclusionpercutaneouscoronaryinterventionfromtheraianrajaieiranregistry AT atafirouzi outcomesofchronictotalocclusionpercutaneouscoronaryinterventionfromtheraianrajaieiranregistry AT mohammadjavadalemzadehansari outcomesofchronictotalocclusionpercutaneouscoronaryinterventionfromtheraianrajaieiranregistry AT alfredorgalassi outcomesofchronictotalocclusionpercutaneouscoronaryinterventionfromtheraianrajaieiranregistry |