Progressive Multifocal Leukoencephalopathy Diagnosed by Metagenomic Next-Generation Sequencing of Cerebrospinal Fluid in an HIV Patient

Progressive Multifocal Leukoencephalopathy Diagnosed by Metagenomic Next-Generation Sequencing of Cerebrospinal Fluid in an HIV Patient

Metagenomic next-generation sequencing (mNGS) is a novel approach to identify pathogens undetected by conventional methods. Herein, we report a case in which mNGS was used to identify JC virus from the cerebrospinal fluid sample of an HIV positive patient with progressive multifocal leukoencephalopa...

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Bibliographic Details
Main Authors: Huan Xia, Yuanlin Guan, Silvère D. Zaongo, Han Xia, Ziyu Wang, Zhongfang Yan, Ping Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Neurology
Subjects:
progressive multifocal leukoencephalopathy
metagenomic next-generation sequencing
cerebrospinal fluid
HIV
PML
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.01202/full

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