Fagonia stabilized gold nanoparticles as antimicrobial agents
In this study, gold nanoparticles (GNPs) were synthesized using an aqueous extract of Fagonia , as a stabilizing and reducing agent, applying the green approach. The phytochemicals present in Fagonia extract are responsible for the creation of GNPs. The reaction kinetics of Fagonia stabilized GNPs (...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
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IOP Publishing
2021-01-01
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Series: | Materials Research Express |
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Online Access: | https://doi.org/10.1088/2053-1591/ac1bcb |
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author | Rukhsana Mariam Gul Naz Muhammad Ramzan Muhammad Naeem Anjum Shazia Anjum Muhammad Abdullah |
author_facet | Rukhsana Mariam Gul Naz Muhammad Ramzan Muhammad Naeem Anjum Shazia Anjum Muhammad Abdullah |
author_sort | Rukhsana Mariam |
collection | DOAJ |
description | In this study, gold nanoparticles (GNPs) were synthesized using an aqueous extract of Fagonia , as a stabilizing and reducing agent, applying the green approach. The phytochemicals present in Fagonia extract are responsible for the creation of GNPs. The reaction kinetics of Fagonia stabilized GNPs (FGNPs) was observed through the optical absorption spectra and the absorption maxima occurred at 547 nm. The face-centered cubic (FCC) nature of the GNPs was analyzed by the XRD pattern and average crystallite size ( D ) was measured about 10 nm. TEM images showed roughly spherical shapes of FGNPs. Evidence of successful formation of FGNPs was revealed by FTIR spectra of pure Fagonia and FGNPs. Fluorescence spectroscopic analysis of FGNPs exhibited a sharp red emission at about 700 nm. TGA technique showed a weight loss of about 19.3% in FGNPs confirming the presence of ligand onto the surface of GNPs. As-synthesized GNPs were investigated for their biomedical application i.e. antimicrobial activities against E. coli and Cocci . The eco-friendly prepared GNPs could play an important role in antimicrobial applications and their visible emission property may suggest the use of such FGNPs as potential biomarkers. |
first_indexed | 2024-03-12T15:42:55Z |
format | Article |
id | doaj.art-3404e914561b401c897ff1bdaf6aa8de |
institution | Directory Open Access Journal |
issn | 2053-1591 |
language | English |
last_indexed | 2024-03-12T15:42:55Z |
publishDate | 2021-01-01 |
publisher | IOP Publishing |
record_format | Article |
series | Materials Research Express |
spelling | doaj.art-3404e914561b401c897ff1bdaf6aa8de2023-08-09T15:51:59ZengIOP PublishingMaterials Research Express2053-15912021-01-018808501110.1088/2053-1591/ac1bcbFagonia stabilized gold nanoparticles as antimicrobial agentsRukhsana Mariam0Gul Naz1https://orcid.org/0000-0002-8080-8370Muhammad Ramzan2Muhammad Naeem Anjum3Shazia Anjum4Muhammad Abdullah5Institute of Physics, Faculty of Science, The Islamia University of Bahawalpur , Baghdad-ul-Jadid Campus, Bahawalpur 63100, PakistanInstitute of Physics, Faculty of Science, The Islamia University of Bahawalpur , Baghdad-ul-Jadid Campus, Bahawalpur 63100, PakistanInstitute of Physics, Faculty of Science, The Islamia University of Bahawalpur , Baghdad-ul-Jadid Campus, Bahawalpur 63100, PakistanInstitute of Physics, Faculty of Science, The Islamia University of Bahawalpur , Baghdad-ul-Jadid Campus, Bahawalpur 63100, PakistanInstitute of Chemistry, Faculty of Science, The Islamia University of Bahawalpur , Baghdad-ul-Jadid Campus, Bahawalpur 63100, PakistanCholistan Institute of Desert Studies (CIDS), The Islamia University , Bahawalpur 63100, PakistanIn this study, gold nanoparticles (GNPs) were synthesized using an aqueous extract of Fagonia , as a stabilizing and reducing agent, applying the green approach. The phytochemicals present in Fagonia extract are responsible for the creation of GNPs. The reaction kinetics of Fagonia stabilized GNPs (FGNPs) was observed through the optical absorption spectra and the absorption maxima occurred at 547 nm. The face-centered cubic (FCC) nature of the GNPs was analyzed by the XRD pattern and average crystallite size ( D ) was measured about 10 nm. TEM images showed roughly spherical shapes of FGNPs. Evidence of successful formation of FGNPs was revealed by FTIR spectra of pure Fagonia and FGNPs. Fluorescence spectroscopic analysis of FGNPs exhibited a sharp red emission at about 700 nm. TGA technique showed a weight loss of about 19.3% in FGNPs confirming the presence of ligand onto the surface of GNPs. As-synthesized GNPs were investigated for their biomedical application i.e. antimicrobial activities against E. coli and Cocci . The eco-friendly prepared GNPs could play an important role in antimicrobial applications and their visible emission property may suggest the use of such FGNPs as potential biomarkers.https://doi.org/10.1088/2053-1591/ac1bcbfagonia indicagold nanoparticlesred emissionantimicrobial activitiesE.coli and Cocci |
spellingShingle | Rukhsana Mariam Gul Naz Muhammad Ramzan Muhammad Naeem Anjum Shazia Anjum Muhammad Abdullah Fagonia stabilized gold nanoparticles as antimicrobial agents Materials Research Express fagonia indica gold nanoparticles red emission antimicrobial activities E.coli and Cocci |
title | Fagonia stabilized gold nanoparticles as antimicrobial agents |
title_full | Fagonia stabilized gold nanoparticles as antimicrobial agents |
title_fullStr | Fagonia stabilized gold nanoparticles as antimicrobial agents |
title_full_unstemmed | Fagonia stabilized gold nanoparticles as antimicrobial agents |
title_short | Fagonia stabilized gold nanoparticles as antimicrobial agents |
title_sort | fagonia stabilized gold nanoparticles as antimicrobial agents |
topic | fagonia indica gold nanoparticles red emission antimicrobial activities E.coli and Cocci |
url | https://doi.org/10.1088/2053-1591/ac1bcb |
work_keys_str_mv | AT rukhsanamariam fagoniastabilizedgoldnanoparticlesasantimicrobialagents AT gulnaz fagoniastabilizedgoldnanoparticlesasantimicrobialagents AT muhammadramzan fagoniastabilizedgoldnanoparticlesasantimicrobialagents AT muhammadnaeemanjum fagoniastabilizedgoldnanoparticlesasantimicrobialagents AT shaziaanjum fagoniastabilizedgoldnanoparticlesasantimicrobialagents AT muhammadabdullah fagoniastabilizedgoldnanoparticlesasantimicrobialagents |