Ivermectin induced Steven–Johnsons syndrome: case report
Abstract Background Stevens–Johnson syndrome is one of the manifestations of mucocutaneous adverse drug reactions. Although antimicrobials are responsible for greater than 50% of these adverse drug reactions, there is no documented case implicating ivermectin as the culprit. Case summary A 38 year o...
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| Format: | Article |
| Language: | English |
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BMC
2017-05-01
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| Series: | BMC Research Notes |
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| Online Access: | http://link.springer.com/article/10.1186/s13104-017-2500-5 |
| _version_ | 1818251540348010496 |
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| author | Desmond Aroke Diego Nitcheu Tchouakam Alexis Tazinya Awungia Sylvester Yari Mapoh Stewart Ndutard Ngassa Benjamin Momo Kadia |
| author_facet | Desmond Aroke Diego Nitcheu Tchouakam Alexis Tazinya Awungia Sylvester Yari Mapoh Stewart Ndutard Ngassa Benjamin Momo Kadia |
| author_sort | Desmond Aroke |
| collection | DOAJ |
| description | Abstract Background Stevens–Johnson syndrome is one of the manifestations of mucocutaneous adverse drug reactions. Although antimicrobials are responsible for greater than 50% of these adverse drug reactions, there is no documented case implicating ivermectin as the culprit. Case summary A 38 year old adult Cameroonian male presented to our health facility with facial rash, painful oral sores, black eschars on lips and red tearing eyes 3 days following ingestion of ivermectin received during a nationwide anti-filarial campaign. He had no known chronic illness, no known allergies and was not on any medications prior to the campaign. Physical examination revealed discharging erythematous eyes, crusted and blister-like lesions with cracks on his lips and oral mucosa. His laboratory tests were unremarkable but for a positive Human Immunodeficiency Virus (HIV) test. A diagnosis of Ivermectin induced Stevens–Johnson syndrome in a newly diagnosed HIV patient was made. The patient was managed with supportive therapy and the evolution thereafter was favourable. Conclusion Stevens–Johnson syndrome is a potential side effect of ivermectin and susceptibility to this adverse effect may be increased in HIV infection. |
| first_indexed | 2024-12-12T16:09:54Z |
| format | Article |
| id | doaj.art-340becb81f1f45808d238efaf3b0cab9 |
| institution | Directory Open Access Journal |
| issn | 1756-0500 |
| language | English |
| last_indexed | 2024-12-12T16:09:54Z |
| publishDate | 2017-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Research Notes |
| spelling | doaj.art-340becb81f1f45808d238efaf3b0cab92022-12-22T00:19:12ZengBMCBMC Research Notes1756-05002017-05-011011410.1186/s13104-017-2500-5Ivermectin induced Steven–Johnsons syndrome: case reportDesmond Aroke0Diego Nitcheu Tchouakam1Alexis Tazinya Awungia2Sylvester Yari Mapoh3Stewart Ndutard Ngassa4Benjamin Momo Kadia5Nkwen Baptist Health CenterHealth and Human Development (2HD) Research GroupMboppi Baptist HospitalUniversite Libre BrusselsBali Kumbat Sub-Divisional HospitalPresbyterian General Hospital Acha-TugiAbstract Background Stevens–Johnson syndrome is one of the manifestations of mucocutaneous adverse drug reactions. Although antimicrobials are responsible for greater than 50% of these adverse drug reactions, there is no documented case implicating ivermectin as the culprit. Case summary A 38 year old adult Cameroonian male presented to our health facility with facial rash, painful oral sores, black eschars on lips and red tearing eyes 3 days following ingestion of ivermectin received during a nationwide anti-filarial campaign. He had no known chronic illness, no known allergies and was not on any medications prior to the campaign. Physical examination revealed discharging erythematous eyes, crusted and blister-like lesions with cracks on his lips and oral mucosa. His laboratory tests were unremarkable but for a positive Human Immunodeficiency Virus (HIV) test. A diagnosis of Ivermectin induced Stevens–Johnson syndrome in a newly diagnosed HIV patient was made. The patient was managed with supportive therapy and the evolution thereafter was favourable. Conclusion Stevens–Johnson syndrome is a potential side effect of ivermectin and susceptibility to this adverse effect may be increased in HIV infection.http://link.springer.com/article/10.1186/s13104-017-2500-5IvermectinStevens–Johnson syndrome (SJS)Human immunodeficiency virus (HIV) |
| spellingShingle | Desmond Aroke Diego Nitcheu Tchouakam Alexis Tazinya Awungia Sylvester Yari Mapoh Stewart Ndutard Ngassa Benjamin Momo Kadia Ivermectin induced Steven–Johnsons syndrome: case report BMC Research Notes Ivermectin Stevens–Johnson syndrome (SJS) Human immunodeficiency virus (HIV) |
| title | Ivermectin induced Steven–Johnsons syndrome: case report |
| title_full | Ivermectin induced Steven–Johnsons syndrome: case report |
| title_fullStr | Ivermectin induced Steven–Johnsons syndrome: case report |
| title_full_unstemmed | Ivermectin induced Steven–Johnsons syndrome: case report |
| title_short | Ivermectin induced Steven–Johnsons syndrome: case report |
| title_sort | ivermectin induced steven johnsons syndrome case report |
| topic | Ivermectin Stevens–Johnson syndrome (SJS) Human immunodeficiency virus (HIV) |
| url | http://link.springer.com/article/10.1186/s13104-017-2500-5 |
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