Agoraphobia and panic attacks complicated by primary aldosteronism improved by treatment with eplerenone: a case report

Abstract Background Primary aldosteronism (PA) is an adrenal gland disease, that induces increased secretion of the mineralocorticoid, aldosterone, resulting in symptoms such as hypertension. This study reports a patient with agoraphobia and panic attacks, associated with PA. This patient’s psychiat...

Full description

Bibliographic Details
Main Authors: Reoto Kijima, Hirofumi Tesen, Ryohei Igata, Naomichi Okamoto, Reiji Yoshimura
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Psychiatry
Subjects:
Online Access:https://doi.org/10.1186/s12888-023-05275-w
_version_ 1797647178667130880
author Reoto Kijima
Hirofumi Tesen
Ryohei Igata
Naomichi Okamoto
Reiji Yoshimura
author_facet Reoto Kijima
Hirofumi Tesen
Ryohei Igata
Naomichi Okamoto
Reiji Yoshimura
author_sort Reoto Kijima
collection DOAJ
description Abstract Background Primary aldosteronism (PA) is an adrenal gland disease, that induces increased secretion of the mineralocorticoid, aldosterone, resulting in symptoms such as hypertension. This study reports a patient with agoraphobia and panic attacks, associated with PA. This patient’s psychiatric symptoms improved after treatment with eplerenone, a mineralocorticoid receptor antagonist. Case presentation The patient was a 40-year-old female with agoraphobia, which refers to the irrational fear of situations that may cause anxiety, and panic attacks characterized by profuse sweating, palpitations, and generalized weakness. She was diagnosed with hypertension from PA. Subsequently, she received treatment with eplerenone, which improved her agoraphobia and panic attacks. Conclusions There have been no previous reports on PA associated with agoraphobia and panic attacks that improved with pharmacotherapy. Patients with agoraphobia and panic attacks should be evaluated for PA. In patients with PA, pharmacotherapy with eplerenone should be considered.
first_indexed 2024-03-11T15:13:29Z
format Article
id doaj.art-340c3651900a4715aaca2d98da4c40f8
institution Directory Open Access Journal
issn 1471-244X
language English
last_indexed 2024-03-11T15:13:29Z
publishDate 2023-10-01
publisher BMC
record_format Article
series BMC Psychiatry
spelling doaj.art-340c3651900a4715aaca2d98da4c40f82023-10-29T12:31:56ZengBMCBMC Psychiatry1471-244X2023-10-012311310.1186/s12888-023-05275-wAgoraphobia and panic attacks complicated by primary aldosteronism improved by treatment with eplerenone: a case reportReoto Kijima0Hirofumi Tesen1Ryohei Igata2Naomichi Okamoto3Reiji Yoshimura4Department of Psychiatry, University of Occupational and Environmental HealthDepartment of Psychiatry, University of Occupational and Environmental HealthDepartment of Psychiatry, University of Occupational and Environmental HealthDepartment of Psychiatry, University of Occupational and Environmental HealthDepartment of Psychiatry, University of Occupational and Environmental HealthAbstract Background Primary aldosteronism (PA) is an adrenal gland disease, that induces increased secretion of the mineralocorticoid, aldosterone, resulting in symptoms such as hypertension. This study reports a patient with agoraphobia and panic attacks, associated with PA. This patient’s psychiatric symptoms improved after treatment with eplerenone, a mineralocorticoid receptor antagonist. Case presentation The patient was a 40-year-old female with agoraphobia, which refers to the irrational fear of situations that may cause anxiety, and panic attacks characterized by profuse sweating, palpitations, and generalized weakness. She was diagnosed with hypertension from PA. Subsequently, she received treatment with eplerenone, which improved her agoraphobia and panic attacks. Conclusions There have been no previous reports on PA associated with agoraphobia and panic attacks that improved with pharmacotherapy. Patients with agoraphobia and panic attacks should be evaluated for PA. In patients with PA, pharmacotherapy with eplerenone should be considered.https://doi.org/10.1186/s12888-023-05275-wAgoraphobiaPanic AttacksPrimary aldosteronismMineralocorticoid
spellingShingle Reoto Kijima
Hirofumi Tesen
Ryohei Igata
Naomichi Okamoto
Reiji Yoshimura
Agoraphobia and panic attacks complicated by primary aldosteronism improved by treatment with eplerenone: a case report
BMC Psychiatry
Agoraphobia
Panic Attacks
Primary aldosteronism
Mineralocorticoid
title Agoraphobia and panic attacks complicated by primary aldosteronism improved by treatment with eplerenone: a case report
title_full Agoraphobia and panic attacks complicated by primary aldosteronism improved by treatment with eplerenone: a case report
title_fullStr Agoraphobia and panic attacks complicated by primary aldosteronism improved by treatment with eplerenone: a case report
title_full_unstemmed Agoraphobia and panic attacks complicated by primary aldosteronism improved by treatment with eplerenone: a case report
title_short Agoraphobia and panic attacks complicated by primary aldosteronism improved by treatment with eplerenone: a case report
title_sort agoraphobia and panic attacks complicated by primary aldosteronism improved by treatment with eplerenone a case report
topic Agoraphobia
Panic Attacks
Primary aldosteronism
Mineralocorticoid
url https://doi.org/10.1186/s12888-023-05275-w
work_keys_str_mv AT reotokijima agoraphobiaandpanicattackscomplicatedbyprimaryaldosteronismimprovedbytreatmentwitheplerenoneacasereport
AT hirofumitesen agoraphobiaandpanicattackscomplicatedbyprimaryaldosteronismimprovedbytreatmentwitheplerenoneacasereport
AT ryoheiigata agoraphobiaandpanicattackscomplicatedbyprimaryaldosteronismimprovedbytreatmentwitheplerenoneacasereport
AT naomichiokamoto agoraphobiaandpanicattackscomplicatedbyprimaryaldosteronismimprovedbytreatmentwitheplerenoneacasereport
AT reijiyoshimura agoraphobiaandpanicattackscomplicatedbyprimaryaldosteronismimprovedbytreatmentwitheplerenoneacasereport