Thermo-sensitive hydrogel-mediated locally sequential release of doxorubicin and palbociclib for chemo-immunotherapy of osteosarcoma
Traditional cytotoxic drugs induce immunogenic cell death (ICD) of tumor cells to trigger anti-tumor immunity. Unfortunately, the presence of immunosuppressive cells such as regulatory T cells (Tregs) in tumor microenvironment offsets part of anti-tumor immunity. In this work, we engineered a methox...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-12-01
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| Series: | Materials & Design |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S026412752200987X |