Hearing loss among patients with Turner's syndrome: literature review
INTRODUCTION: Turner's syndrome (TS) is caused by a partial or total deletion of an X chromosome, occurring in 1:2,000 to 1:5,000 live born females. Hearing loss is one of its major clinical manifestations. However, there are few studies investigating this problem. OBJECTIVES: To review th...
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| Format: | Article |
| Language: | English |
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Elsevier
2014-06-01
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| Series: | Brazilian Journal of Otorhinolaryngology |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942014000300257&lng=en&tlng=en |
| _version_ | 1818360465276796928 |
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| author | Cresio Alves Conceição Silva Oliveira |
| author_facet | Cresio Alves Conceição Silva Oliveira |
| author_sort | Cresio Alves |
| collection | DOAJ |
| description | INTRODUCTION: Turner's syndrome (TS) is caused by a partial or total deletion of an X chromosome, occurring in 1:2,000 to 1:5,000 live born females. Hearing loss is one of its major clinical manifestations. However, there are few studies investigating this problem. OBJECTIVES: To review the current knowledge regarding the epidemiology, etiology, clinical manifestations and diagnosis of hearing impairment in patients with TS. METHODS: A bibliographic search was performed in the Medline and Lilacs databanks (1980-2012) to identify the main papers associating Turner's syndrome, hearing impairment and its clinical outcomes. CONCLUSIONS: Recurrent otitis media, dysfunction of the Eustachian tube, conductive hearing loss during infancy and sensorineural hearing loss in adolescence are the audiologic disorders more common in ST. The karyotype appears to be important in the hearing loss, with studies demonstrating an increased prevalence in patients with monosomy 45,X or isochromosome 46,i(Xq). Morphologic studies of the cochlea are necessary to help out in the clarifying the etiology of the sensorineural hearing loss. |
| first_indexed | 2024-12-13T21:01:13Z |
| format | Article |
| id | doaj.art-340fc64f2b894dab9efff1e4282de889 |
| institution | Directory Open Access Journal |
| issn | 1808-8686 |
| language | English |
| last_indexed | 2024-12-13T21:01:13Z |
| publishDate | 2014-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Brazilian Journal of Otorhinolaryngology |
| spelling | doaj.art-340fc64f2b894dab9efff1e4282de8892022-12-21T23:31:35ZengElsevierBrazilian Journal of Otorhinolaryngology1808-86862014-06-0180325726310.1016/j.bjorl.2013.08.002S1808-86942014000300257Hearing loss among patients with Turner's syndrome: literature reviewCresio AlvesConceição Silva OliveiraINTRODUCTION: Turner's syndrome (TS) is caused by a partial or total deletion of an X chromosome, occurring in 1:2,000 to 1:5,000 live born females. Hearing loss is one of its major clinical manifestations. However, there are few studies investigating this problem. OBJECTIVES: To review the current knowledge regarding the epidemiology, etiology, clinical manifestations and diagnosis of hearing impairment in patients with TS. METHODS: A bibliographic search was performed in the Medline and Lilacs databanks (1980-2012) to identify the main papers associating Turner's syndrome, hearing impairment and its clinical outcomes. CONCLUSIONS: Recurrent otitis media, dysfunction of the Eustachian tube, conductive hearing loss during infancy and sensorineural hearing loss in adolescence are the audiologic disorders more common in ST. The karyotype appears to be important in the hearing loss, with studies demonstrating an increased prevalence in patients with monosomy 45,X or isochromosome 46,i(Xq). Morphologic studies of the cochlea are necessary to help out in the clarifying the etiology of the sensorineural hearing loss.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942014000300257&lng=en&tlng=enSíndrome de TurnerPerda auditivaOtopatias |
| spellingShingle | Cresio Alves Conceição Silva Oliveira Hearing loss among patients with Turner's syndrome: literature review Brazilian Journal of Otorhinolaryngology Síndrome de Turner Perda auditiva Otopatias |
| title | Hearing loss among patients with Turner's syndrome: literature review |
| title_full | Hearing loss among patients with Turner's syndrome: literature review |
| title_fullStr | Hearing loss among patients with Turner's syndrome: literature review |
| title_full_unstemmed | Hearing loss among patients with Turner's syndrome: literature review |
| title_short | Hearing loss among patients with Turner's syndrome: literature review |
| title_sort | hearing loss among patients with turner s syndrome literature review |
| topic | Síndrome de Turner Perda auditiva Otopatias |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942014000300257&lng=en&tlng=en |
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