Simplified ChIP-exo assays
While ChIP-exo is low noise and highly informative regarding genome-wide binding proteins, libraries are difficult to construct. Here the authors present a simplified ChIP-exo method for high-resolution detection of interactions.
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2018-07-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-018-05265-7 |
| _version_ | 1818435850829037568 |
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| author | Matthew J. Rossi William K. M. Lai B. Franklin Pugh |
| author_facet | Matthew J. Rossi William K. M. Lai B. Franklin Pugh |
| author_sort | Matthew J. Rossi |
| collection | DOAJ |
| description | While ChIP-exo is low noise and highly informative regarding genome-wide binding proteins, libraries are difficult to construct. Here the authors present a simplified ChIP-exo method for high-resolution detection of interactions. |
| first_indexed | 2024-12-14T16:59:26Z |
| format | Article |
| id | doaj.art-34102353774e422985f66199e415101b |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-14T16:59:26Z |
| publishDate | 2018-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-34102353774e422985f66199e415101b2022-12-21T22:53:53ZengNature PortfolioNature Communications2041-17232018-07-019111310.1038/s41467-018-05265-7Simplified ChIP-exo assaysMatthew J. Rossi0William K. M. Lai1B. Franklin Pugh2Center for Eukaryotic Gene Regulation, Department of Biochemistry and Molecular Biology, The Pennsylvania State UniversityCenter for Eukaryotic Gene Regulation, Department of Biochemistry and Molecular Biology, The Pennsylvania State UniversityCenter for Eukaryotic Gene Regulation, Department of Biochemistry and Molecular Biology, The Pennsylvania State UniversityWhile ChIP-exo is low noise and highly informative regarding genome-wide binding proteins, libraries are difficult to construct. Here the authors present a simplified ChIP-exo method for high-resolution detection of interactions.https://doi.org/10.1038/s41467-018-05265-7 |
| spellingShingle | Matthew J. Rossi William K. M. Lai B. Franklin Pugh Simplified ChIP-exo assays Nature Communications |
| title | Simplified ChIP-exo assays |
| title_full | Simplified ChIP-exo assays |
| title_fullStr | Simplified ChIP-exo assays |
| title_full_unstemmed | Simplified ChIP-exo assays |
| title_short | Simplified ChIP-exo assays |
| title_sort | simplified chip exo assays |
| url | https://doi.org/10.1038/s41467-018-05265-7 |
| work_keys_str_mv | AT matthewjrossi simplifiedchipexoassays AT williamkmlai simplifiedchipexoassays AT bfranklinpugh simplifiedchipexoassays |