Advances in Understanding the Role of NRF2 in Liver Pathophysiology and Its Relationship with Hepatic-Specific Cyclooxygenase-2 Expression

Advances in Understanding the Role of NRF2 in Liver Pathophysiology and Its Relationship with Hepatic-Specific Cyclooxygenase-2 Expression

Oxidative stress and inflammation play an important role in the pathophysiological changes of liver diseases. Nuclear factor erythroid 2-related factor 2 (NRF2) is a transcription factor that positively regulates the basal and inducible expression of a large battery of cytoprotective genes, thus pla...

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Bibliographic Details
Main Authors: Marina Fuertes-Agudo, María Luque-Tévar, Carme Cucarella, Paloma Martín-Sanz, Marta Casado
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Antioxidants
Subjects:
liver diseases
NRF2
COX-2
oxidative stress
inflammation
Online Access:https://www.mdpi.com/2076-3921/12/8/1491

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