NK-, NKT- and CD8-Derived IFNγ Drives Myeloid Cell Activation and Erythrophagocytosis, Resulting in Trypanosomosis-Associated Acute Anemia.

NK-, NKT- and CD8-Derived IFNγ Drives Myeloid Cell Activation and Erythrophagocytosis, Resulting in Trypanosomosis-Associated Acute Anemia.

African trypanosomes are the causative agents of Human African Trypanosomosis (HAT/Sleeping Sickness) and Animal African Trypanosomosis (AAT/Nagana). A common hallmark of African trypanosome infections is inflammation. In murine trypanosomosis, the onset of inflammation occurs rapidly after infectio...

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Bibliographic Details
Main Authors: Jennifer Cnops, Carl De Trez, Benoit Stijlemans, Jiri Keirsse, Florence Kauffmann, Mark Barkhuizen, Roanne Keeton, Louis Boon, Frank Brombacher, Stefan Magez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-06-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4466398?pdf=render

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