Fully covered metallic stents for anastomotic biliary strictures after living donor liver transplantation

Abstract Objectives Anastomotic biliary strictures (ABSs) are common complications following living donor liver transplantation (LDLT). We evaluated the feasibility of a novel removable, intraductal, fully covered, self‐expandable metallic stent (FCSEMS) for the treatment of ABSs following LDLT. Met...

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Main Authors: Naohiro Komatsu, Eisuke Ozawa, Masanori Fukushima, Hironori Sawase, Kazuyoshi Nagata, Satoshi Miuma, Hisamitsu Miyaaki, Akihiko Soyama, Masaaki Hidaka, Susumu Eguchi, Kazuhiko Nakao
Format: Article
Language:English
Published: Wiley 2023-04-01
Series:DEN Open
Subjects:
Online Access:https://doi.org/10.1002/deo2.225
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author Naohiro Komatsu
Eisuke Ozawa
Masanori Fukushima
Hironori Sawase
Kazuyoshi Nagata
Satoshi Miuma
Hisamitsu Miyaaki
Akihiko Soyama
Masaaki Hidaka
Susumu Eguchi
Kazuhiko Nakao
author_facet Naohiro Komatsu
Eisuke Ozawa
Masanori Fukushima
Hironori Sawase
Kazuyoshi Nagata
Satoshi Miuma
Hisamitsu Miyaaki
Akihiko Soyama
Masaaki Hidaka
Susumu Eguchi
Kazuhiko Nakao
author_sort Naohiro Komatsu
collection DOAJ
description Abstract Objectives Anastomotic biliary strictures (ABSs) are common complications following living donor liver transplantation (LDLT). We evaluated the feasibility of a novel removable, intraductal, fully covered, self‐expandable metallic stent (FCSEMS) for the treatment of ABSs following LDLT. Methods Nine patients with duct‐to‐duct ABSs that developed following LDLT were prospectively enrolled in this study. We placed a short FCSEMS with a long lasso and middle waist formation in each patient's ABS above the papilla and removed it 16 weeks later. Results The FCSEMS placements were successful in all nine cases. Four patients experienced mild cholangitis, which was resolved with conservative treatment. Additionally, there was one case of distal migration. The FCSEMSs were successfully removed from all the patients, and the clinical success rate was 100%. Stricture recurrence occurred in one (11.1%) patient during the follow‐up period. Limitations The small number and lack of comparison with other types of FCSEMSs and plastic stents. Conclusions Intraductal placement of FCSEMSs is useful for treating refractory ABSs after LDLT, although further studies are required with larger sample sizes.
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spelling doaj.art-3416ac3fa4c747de985ea60908ba28982023-04-29T05:12:57ZengWileyDEN Open2692-46092023-04-0131n/an/a10.1002/deo2.225Fully covered metallic stents for anastomotic biliary strictures after living donor liver transplantationNaohiro Komatsu0Eisuke Ozawa1Masanori Fukushima2Hironori Sawase3Kazuyoshi Nagata4Satoshi Miuma5Hisamitsu Miyaaki6Akihiko Soyama7Masaaki Hidaka8Susumu Eguchi9Kazuhiko Nakao10Department of Gastroenterology and Hepatology Nagasaki University Graduate School of Biomedical Sciences Nagasaki JapanDepartment of Gastroenterology and Hepatology Nagasaki University Graduate School of Biomedical Sciences Nagasaki JapanDepartment of Gastroenterology and Hepatology Nagasaki University Graduate School of Biomedical Sciences Nagasaki JapanDepartment of Gastroenterology and Hepatology Nagasaki University Graduate School of Biomedical Sciences Nagasaki JapanDepartment of Gastroenterology and Hepatology Nagasaki University Graduate School of Biomedical Sciences Nagasaki JapanDepartment of Gastroenterology and Hepatology Nagasaki University Graduate School of Biomedical Sciences Nagasaki JapanDepartment of Gastroenterology and Hepatology Nagasaki University Graduate School of Biomedical Sciences Nagasaki JapanDepartment of Surgery Nagasaki University Graduate School of Biomedical Sciences Nagasaki JapanDepartment of Surgery Nagasaki University Graduate School of Biomedical Sciences Nagasaki JapanDepartment of Surgery Nagasaki University Graduate School of Biomedical Sciences Nagasaki JapanDepartment of Gastroenterology and Hepatology Nagasaki University Graduate School of Biomedical Sciences Nagasaki JapanAbstract Objectives Anastomotic biliary strictures (ABSs) are common complications following living donor liver transplantation (LDLT). We evaluated the feasibility of a novel removable, intraductal, fully covered, self‐expandable metallic stent (FCSEMS) for the treatment of ABSs following LDLT. Methods Nine patients with duct‐to‐duct ABSs that developed following LDLT were prospectively enrolled in this study. We placed a short FCSEMS with a long lasso and middle waist formation in each patient's ABS above the papilla and removed it 16 weeks later. Results The FCSEMS placements were successful in all nine cases. Four patients experienced mild cholangitis, which was resolved with conservative treatment. Additionally, there was one case of distal migration. The FCSEMSs were successfully removed from all the patients, and the clinical success rate was 100%. Stricture recurrence occurred in one (11.1%) patient during the follow‐up period. Limitations The small number and lack of comparison with other types of FCSEMSs and plastic stents. Conclusions Intraductal placement of FCSEMSs is useful for treating refractory ABSs after LDLT, although further studies are required with larger sample sizes.https://doi.org/10.1002/deo2.225anastomotic biliary stricturefully covered self‐expandable metallic stentliving donor liver transplantationplastic stentcholangitis
spellingShingle Naohiro Komatsu
Eisuke Ozawa
Masanori Fukushima
Hironori Sawase
Kazuyoshi Nagata
Satoshi Miuma
Hisamitsu Miyaaki
Akihiko Soyama
Masaaki Hidaka
Susumu Eguchi
Kazuhiko Nakao
Fully covered metallic stents for anastomotic biliary strictures after living donor liver transplantation
DEN Open
anastomotic biliary stricture
fully covered self‐expandable metallic stent
living donor liver transplantation
plastic stent
cholangitis
title Fully covered metallic stents for anastomotic biliary strictures after living donor liver transplantation
title_full Fully covered metallic stents for anastomotic biliary strictures after living donor liver transplantation
title_fullStr Fully covered metallic stents for anastomotic biliary strictures after living donor liver transplantation
title_full_unstemmed Fully covered metallic stents for anastomotic biliary strictures after living donor liver transplantation
title_short Fully covered metallic stents for anastomotic biliary strictures after living donor liver transplantation
title_sort fully covered metallic stents for anastomotic biliary strictures after living donor liver transplantation
topic anastomotic biliary stricture
fully covered self‐expandable metallic stent
living donor liver transplantation
plastic stent
cholangitis
url https://doi.org/10.1002/deo2.225
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