Bacterial Profile of Urinary Tract Infections and Antibiotic Resistance Pattern in a Tertiary Care Hospital

Background: Due to emergence of multidrug resistance, empirical treatment of Urinary tract infections is becoming intricate. Aim: To know the bacteria causing UTI, their antibiogram and possibility of using fosfomycin as an empirical drug. Material and Methods: Urine sample from suspected UTI cases...

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Bibliographic Details
Main Authors: Mangalgi Smita S, Sanjay S Wavare, Shivali Gajul, Annapurna G Sajjan
Format: Article
Language:English
Published: Light House Polyclinic Mangalore 2020-02-01
Series:Online Journal of Health & Allied Sciences
Subjects:
Online Access:https://www.ojhas.org/issue72/2019-4-6.html
Description
Summary:Background: Due to emergence of multidrug resistance, empirical treatment of Urinary tract infections is becoming intricate. Aim: To know the bacteria causing UTI, their antibiogram and possibility of using fosfomycin as an empirical drug. Material and Methods: Urine sample from suspected UTI cases were cultured by standard method. Identification of bacterial isolate, antimicrobial susceptibility and ESBL production was performed by standard protocol. Results: Of the 1674 urine samples 529 samples showed significant growth of which 386 were Gram negative bacilli, 107 Gram positive cocci and 36 Candida species. Most prevalent pathogens were E. coli (47.4%) among the Gram negative group and Enterococci (13%) among the Gram positives. A good number of bacteria were susceptible to fosfomycin. Conclusions: Routine surveillance studies are needed to have knowledge about the most effective empirical treatment. Fosfomycin looms out as the drug of choice for empirical treatment of UTI in this area.
ISSN:0972-5997
0972-5997