Polysaccharide Regulation of Intestinal Flora: A Viable Approach to Maintaining Normal Cognitive Performance and Treating Depression
The intestinal tract of a healthy body is home to a large variety and number of microorganisms that will affect every aspect of the host’s life. In recent years, polysaccharides have been found to be an important factor affecting intestinal flora. Polysaccharides are widely found in nature and play...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-03-01
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| Series: | Frontiers in Microbiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2022.807076/full |
| _version_ | 1818720678080151552 |
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| author | Xinzhou Wang Lu Cheng Yanan Liu Ruilin Zhang Zufang Wu Peifang Weng Peng Zhang Peng Zhang Xin Zhang |
| author_facet | Xinzhou Wang Lu Cheng Yanan Liu Ruilin Zhang Zufang Wu Peifang Weng Peng Zhang Peng Zhang Xin Zhang |
| author_sort | Xinzhou Wang |
| collection | DOAJ |
| description | The intestinal tract of a healthy body is home to a large variety and number of microorganisms that will affect every aspect of the host’s life. In recent years, polysaccharides have been found to be an important factor affecting intestinal flora. Polysaccharides are widely found in nature and play a key role in the life activities of living organisms. In the intestinal tract of living organisms, polysaccharides have many important functions, such as preventing the imbalance of intestinal flora and maintaining the integrity of the intestinal barrier. Moreover, recent studies suggest that gut microbes can influence brain health through the brain-gut axis. Therefore, maintaining brain health through polysaccharide modulation of gut flora deserves further study. In this review, we outline the mechanisms by which polysaccharides maintain normal intestinal flora structure, as well as improving cognitive function in the brain via the brain-gut axis by virtue of the intestinal flora. We also highlight the important role that gut microbes play in the pathogenesis of depression and the potential for treating depression through the use of polysaccharides to modulate the intestinal flora. |
| first_indexed | 2024-12-17T20:26:39Z |
| format | Article |
| id | doaj.art-341b7ea7f4cc45ca89e69c1ad876b1f2 |
| institution | Directory Open Access Journal |
| issn | 1664-302X |
| language | English |
| last_indexed | 2024-12-17T20:26:39Z |
| publishDate | 2022-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj.art-341b7ea7f4cc45ca89e69c1ad876b1f22022-12-21T21:33:44ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2022-03-011310.3389/fmicb.2022.807076807076Polysaccharide Regulation of Intestinal Flora: A Viable Approach to Maintaining Normal Cognitive Performance and Treating DepressionXinzhou Wang0Lu Cheng1Yanan Liu2Ruilin Zhang3Zufang Wu4Peifang Weng5Peng Zhang6Peng Zhang7Xin Zhang8Department of Food Science and Engineering, Ningbo University, Ningbo, ChinaDepartment of Food Science, Rutgers, The State University of New Jersey, Newark, NJ, United StatesDepartment of Food Science and Engineering, Ningbo University, Ningbo, ChinaDepartment of Food Science and Engineering, Ningbo University, Ningbo, ChinaDepartment of Food Science and Engineering, Ningbo University, Ningbo, ChinaDepartment of Food Science and Engineering, Ningbo University, Ningbo, ChinaDepartment of Food Science and Engineering, Ningbo University, Ningbo, ChinaDepartment of Student Affairs, Xinyang Normal University, Xinyang, ChinaDepartment of Food Science and Engineering, Ningbo University, Ningbo, ChinaThe intestinal tract of a healthy body is home to a large variety and number of microorganisms that will affect every aspect of the host’s life. In recent years, polysaccharides have been found to be an important factor affecting intestinal flora. Polysaccharides are widely found in nature and play a key role in the life activities of living organisms. In the intestinal tract of living organisms, polysaccharides have many important functions, such as preventing the imbalance of intestinal flora and maintaining the integrity of the intestinal barrier. Moreover, recent studies suggest that gut microbes can influence brain health through the brain-gut axis. Therefore, maintaining brain health through polysaccharide modulation of gut flora deserves further study. In this review, we outline the mechanisms by which polysaccharides maintain normal intestinal flora structure, as well as improving cognitive function in the brain via the brain-gut axis by virtue of the intestinal flora. We also highlight the important role that gut microbes play in the pathogenesis of depression and the potential for treating depression through the use of polysaccharides to modulate the intestinal flora.https://www.frontiersin.org/articles/10.3389/fmicb.2022.807076/fullpolysaccharidesintestinal florabrain-gut axiscognitivedepression |
| spellingShingle | Xinzhou Wang Lu Cheng Yanan Liu Ruilin Zhang Zufang Wu Peifang Weng Peng Zhang Peng Zhang Xin Zhang Polysaccharide Regulation of Intestinal Flora: A Viable Approach to Maintaining Normal Cognitive Performance and Treating Depression Frontiers in Microbiology polysaccharides intestinal flora brain-gut axis cognitive depression |
| title | Polysaccharide Regulation of Intestinal Flora: A Viable Approach to Maintaining Normal Cognitive Performance and Treating Depression |
| title_full | Polysaccharide Regulation of Intestinal Flora: A Viable Approach to Maintaining Normal Cognitive Performance and Treating Depression |
| title_fullStr | Polysaccharide Regulation of Intestinal Flora: A Viable Approach to Maintaining Normal Cognitive Performance and Treating Depression |
| title_full_unstemmed | Polysaccharide Regulation of Intestinal Flora: A Viable Approach to Maintaining Normal Cognitive Performance and Treating Depression |
| title_short | Polysaccharide Regulation of Intestinal Flora: A Viable Approach to Maintaining Normal Cognitive Performance and Treating Depression |
| title_sort | polysaccharide regulation of intestinal flora a viable approach to maintaining normal cognitive performance and treating depression |
| topic | polysaccharides intestinal flora brain-gut axis cognitive depression |
| url | https://www.frontiersin.org/articles/10.3389/fmicb.2022.807076/full |
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