Non-Antigenic Modulation of Antigen Receptor (TCR) Cβ-FG Loop Modulates Signalling: Implications of External Factors Influencing T-Cell Responses

Non-Antigenic Modulation of Antigen Receptor (TCR) Cβ-FG Loop Modulates Signalling: Implications of External Factors Influencing T-Cell Responses

T-cell recognition of antigens is complex, leading to biochemical and cellular events that impart both specific and targeted immune responses. The end result is an array of cytokines that facilitate the direction and intensity of the immune reaction—such as T-cell proliferation, differentiation, mac...

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Bibliographic Details
Main Authors: Nicholas Manolios, Son Pham, Guojiang Hou, Jonathan Du, Camelia Quek, David Hibbs
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
T-cell antigen receptor
computer modelling
in silico
short chain fatty acids
T-cell signalling
environmental factors
Online Access:https://www.mdpi.com/1422-0067/24/11/9334

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