Complex ultrasound diagnostic assessment of the results of neoadjuvant chemotherapy for locally advanced cervical cancer (Stages IIB–IIIB)

Background. Current complex ultrasound diagnosis using novel imaging techniques can assess, to a high accuracy, different tumor parameters during neoadjuvant chemotherapy (NCT) for locally advanced cervical cancer (CC) (Stages IIB–IIB). This assessment is very important and necessary to define furth...

Full description

Bibliographic Details
Main Authors: L. A. Ashrafyan, O. I. Aleshikova, N. A. Babaeva, I. B. Antonova, S. V. Ivashina, S. L. Vashakmadze, A. A. Myagkova, T. A. Motskobili
Format: Article
Language:Russian
Published: ABV-press 2015-07-01
Series:Опухоли женской репродуктивной системы
Subjects:
Online Access:https://ojrs.abvpress.ru/ojrs/article/view/438
_version_ 1826557263057256448
author L. A. Ashrafyan
O. I. Aleshikova
N. A. Babaeva
I. B. Antonova
S. V. Ivashina
S. L. Vashakmadze
A. A. Myagkova
T. A. Motskobili
author_facet L. A. Ashrafyan
O. I. Aleshikova
N. A. Babaeva
I. B. Antonova
S. V. Ivashina
S. L. Vashakmadze
A. A. Myagkova
T. A. Motskobili
author_sort L. A. Ashrafyan
collection DOAJ
description Background. Current complex ultrasound diagnosis using novel imaging techniques can assess, to a high accuracy, different tumor parameters during neoadjuvant chemotherapy (NCT) for locally advanced cervical cancer (CC) (Stages IIB–IIB). This assessment is very important and necessary to define further treatment policy.Materials and methods. A total of 199 patients diagnosed with Stages IIB–IIIB CC, including 60 patients with Stage IIB (T2bN0M0), 4 with Stage IIIА (T3aN0M0), and 135 with Stage IIIВ (T2bN1M0, T3aN1M0, T3bN0–1M0) (according to the International Federationof Gynecology and Obstetrics (FIGO) classification), who received NCT at Stage 1 of treatment, were examined. Complex ultrasound study was conducted before treatment initiation and after each NCT cycle. The therapeutic pathomorphism of a tumor was evaluated in surgically treated patients.Results. The criteria have been determined for evaluating the efficiency of NCT for locally advanced CC, which are based on current ultrasonographic techniques including B-mode, Doppler ultrasound (power, spectral, three-dimensional ones), as well as on the results of therapeutic pathomorphism.Conclusion. The criteria for evaluating the efficiency of NCT for CC should be based on current complex ultrasonographic techniques.
first_indexed 2024-04-10T01:56:14Z
format Article
id doaj.art-342338d6ae21471bb60d42485d044d0e
institution Directory Open Access Journal
issn 1994-4098
1999-8627
language Russian
last_indexed 2025-03-14T08:25:49Z
publishDate 2015-07-01
publisher ABV-press
record_format Article
series Опухоли женской репродуктивной системы
spelling doaj.art-342338d6ae21471bb60d42485d044d0e2025-03-02T13:05:33ZrusABV-pressОпухоли женской репродуктивной системы1994-40981999-86272015-07-01112768110.17650/1994-4098-2015-11-2-76-81453Complex ultrasound diagnostic assessment of the results of neoadjuvant chemotherapy for locally advanced cervical cancer (Stages IIB–IIIB)L. A. Ashrafyan0O. I. Aleshikova1N. A. Babaeva2I. B. Antonova3S. V. Ivashina4S. L. Vashakmadze5A. A. Myagkova6T. A. Motskobili7Russian X-ray Radiology Research Center, Ministry of Health of Russia; 86 Profsoyuznaya St., Moscow, 117997, RussiaRussian X-ray Radiology Research Center, Ministry of Health of Russia; 86 Profsoyuznaya St., Moscow, 117997, RussiaRussian X-ray Radiology Research Center, Ministry of Health of Russia; 86 Profsoyuznaya St., Moscow, 117997, RussiaRussian X-ray Radiology Research Center, Ministry of Health of Russia; 86 Profsoyuznaya St., Moscow, 117997, RussiaRussian X-ray Radiology Research Center, Ministry of Health of Russia; 86 Profsoyuznaya St., Moscow, 117997, RussiaRussian X-ray Radiology Research Center, Ministry of Health of Russia; 86 Profsoyuznaya St., Moscow, 117997, RussiaRussian X-ray Radiology Research Center, Ministry of Health of Russia; 86 Profsoyuznaya St., Moscow, 117997, RussiaRussian X-ray Radiology Research Center, Ministry of Health of Russia; 86 Profsoyuznaya St., Moscow, 117997, RussiaBackground. Current complex ultrasound diagnosis using novel imaging techniques can assess, to a high accuracy, different tumor parameters during neoadjuvant chemotherapy (NCT) for locally advanced cervical cancer (CC) (Stages IIB–IIB). This assessment is very important and necessary to define further treatment policy.Materials and methods. A total of 199 patients diagnosed with Stages IIB–IIIB CC, including 60 patients with Stage IIB (T2bN0M0), 4 with Stage IIIА (T3aN0M0), and 135 with Stage IIIВ (T2bN1M0, T3aN1M0, T3bN0–1M0) (according to the International Federationof Gynecology and Obstetrics (FIGO) classification), who received NCT at Stage 1 of treatment, were examined. Complex ultrasound study was conducted before treatment initiation and after each NCT cycle. The therapeutic pathomorphism of a tumor was evaluated in surgically treated patients.Results. The criteria have been determined for evaluating the efficiency of NCT for locally advanced CC, which are based on current ultrasonographic techniques including B-mode, Doppler ultrasound (power, spectral, three-dimensional ones), as well as on the results of therapeutic pathomorphism.Conclusion. The criteria for evaluating the efficiency of NCT for CC should be based on current complex ultrasonographic techniques.https://ojrs.abvpress.ru/ojrs/article/view/438complex ultrasound diagnosissonographydopplerlocally advanced cervical cancerneoadjuvant chemotherapydiagnosistreatment
spellingShingle L. A. Ashrafyan
O. I. Aleshikova
N. A. Babaeva
I. B. Antonova
S. V. Ivashina
S. L. Vashakmadze
A. A. Myagkova
T. A. Motskobili
Complex ultrasound diagnostic assessment of the results of neoadjuvant chemotherapy for locally advanced cervical cancer (Stages IIB–IIIB)
Опухоли женской репродуктивной системы
complex ultrasound diagnosis
sonography
doppler
locally advanced cervical cancer
neoadjuvant chemotherapy
diagnosis
treatment
title Complex ultrasound diagnostic assessment of the results of neoadjuvant chemotherapy for locally advanced cervical cancer (Stages IIB–IIIB)
title_full Complex ultrasound diagnostic assessment of the results of neoadjuvant chemotherapy for locally advanced cervical cancer (Stages IIB–IIIB)
title_fullStr Complex ultrasound diagnostic assessment of the results of neoadjuvant chemotherapy for locally advanced cervical cancer (Stages IIB–IIIB)
title_full_unstemmed Complex ultrasound diagnostic assessment of the results of neoadjuvant chemotherapy for locally advanced cervical cancer (Stages IIB–IIIB)
title_short Complex ultrasound diagnostic assessment of the results of neoadjuvant chemotherapy for locally advanced cervical cancer (Stages IIB–IIIB)
title_sort complex ultrasound diagnostic assessment of the results of neoadjuvant chemotherapy for locally advanced cervical cancer stages iib iiib
topic complex ultrasound diagnosis
sonography
doppler
locally advanced cervical cancer
neoadjuvant chemotherapy
diagnosis
treatment
url https://ojrs.abvpress.ru/ojrs/article/view/438
work_keys_str_mv AT laashrafyan complexultrasounddiagnosticassessmentoftheresultsofneoadjuvantchemotherapyforlocallyadvancedcervicalcancerstagesiibiiib
AT oialeshikova complexultrasounddiagnosticassessmentoftheresultsofneoadjuvantchemotherapyforlocallyadvancedcervicalcancerstagesiibiiib
AT nababaeva complexultrasounddiagnosticassessmentoftheresultsofneoadjuvantchemotherapyforlocallyadvancedcervicalcancerstagesiibiiib
AT ibantonova complexultrasounddiagnosticassessmentoftheresultsofneoadjuvantchemotherapyforlocallyadvancedcervicalcancerstagesiibiiib
AT svivashina complexultrasounddiagnosticassessmentoftheresultsofneoadjuvantchemotherapyforlocallyadvancedcervicalcancerstagesiibiiib
AT slvashakmadze complexultrasounddiagnosticassessmentoftheresultsofneoadjuvantchemotherapyforlocallyadvancedcervicalcancerstagesiibiiib
AT aamyagkova complexultrasounddiagnosticassessmentoftheresultsofneoadjuvantchemotherapyforlocallyadvancedcervicalcancerstagesiibiiib
AT tamotskobili complexultrasounddiagnosticassessmentoftheresultsofneoadjuvantchemotherapyforlocallyadvancedcervicalcancerstagesiibiiib