Differential DNA methylation in Black and White individuals with chronic low back pain enrich different genomic pathways

Differential DNA methylation in Black and White individuals with chronic low back pain enrich different genomic pathways

Compared to Non-Hispanic Whites (NHWs), individuals who self-identify as Non-Hispanic Blacks (NHBs) in the United States experience more severe and disabling chronic low back pain (cLBP). We hypothesized that differences in DNA methylation (DNAm) play a role in racial disparities in cLBP. Purpose: T...

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Bibliographic Details
Main Authors: Edwin N. Aroke, Pamela Jackson, Lingsong Meng, Zhiguang Huo, Demario S. Overstreet, Terence M. Penn, Tammie L. Quinn, Yenisel Cruz-Almeida, Burel R. Goodin
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Neurobiology of Pain
Subjects:
Racial pain disparities
RRBS
Pain mechanisms
Chronic low back pain
Non-specific chronic low back pain
DNA methylation
Online Access:http://www.sciencedirect.com/science/article/pii/S2452073X22000034

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