A comprehensive review of the diagnosis and management of mitral paravalvular leakage
Mitral paravalvular leaks (PVLs) commonly occur in patients with prosthetic valves. Paravalvular defects may be clinically inconsequential and may aggravate hemolysis or cause heart failure through regurgitation. Accordingly, patients may eventually require intervention such as redo surgery or a tra...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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KARE Publishing
2020-11-01
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| Series: | Anatolian Journal of Cardiology |
| Subjects: | |
| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=anatoljcardiol&un=AJC-10018 |
| _version_ | 1797907005809098752 |
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| author | Mustafa Ozan Gürsoy Ahmet Güner Macit Kalçık Emrah Bayam Mehmet Özkan |
| author_facet | Mustafa Ozan Gürsoy Ahmet Güner Macit Kalçık Emrah Bayam Mehmet Özkan |
| author_sort | Mustafa Ozan Gürsoy |
| collection | DOAJ |
| description | Mitral paravalvular leaks (PVLs) commonly occur in patients with prosthetic valves. Paravalvular defects may be clinically inconsequential and may aggravate hemolysis or cause heart failure through regurgitation. Accordingly, patients may eventually require intervention such as redo surgery or a transcatheter closure of the defects. The introduction of purpose-specific closure devices and new steerable catheters has opened a new frontier for the transcatheter PVL closure. This mode of treatment is an initial therapy in most centers with experienced structural heart team. However, head-to-head data comparing two treatment modalities (surgery and transcatheter closure) are limited, and the world-wide experience is based on nonrandomized studies. Multimodality imaging, including three-dimensional transesophageal echocardiography, facilitates the delineation of mitral PVLs and provides essential data that aids the communication between the members of the structural heart team. In the near future, the success of interventional therapies will most probably increase in patients with mitral PVLs with the introduction of hybrid imaging modalities (echocardiography, cardiac computed tomography, and fluoroscopy). In conclusion, this paper summarizes the etiopathogenesis, clinical characteristics, diagnosis, and treatment of mitral PVLs. |
| first_indexed | 2024-04-10T10:29:41Z |
| format | Article |
| id | doaj.art-34326b45f24244298fefa81b31eb1d8f |
| institution | Directory Open Access Journal |
| issn | 2149-2263 |
| language | English |
| last_indexed | 2024-04-10T10:29:41Z |
| publishDate | 2020-11-01 |
| publisher | KARE Publishing |
| record_format | Article |
| series | Anatolian Journal of Cardiology |
| spelling | doaj.art-34326b45f24244298fefa81b31eb1d8f2023-02-15T16:21:10ZengKARE PublishingAnatolian Journal of Cardiology2149-22632020-11-0124635036010.14744/AnatolJCardiol.2020.10018AJC-10018A comprehensive review of the diagnosis and management of mitral paravalvular leakageMustafa Ozan Gürsoy0Ahmet Güner1Macit Kalçık2Emrah Bayam3Mehmet Özkan4Department of Cardiology, İzmir Katip Çelebi University, Atatürk Training and Research Hospital; İzmir-TurkeyDepartment of Cardiology, University of Health Sciences, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital; İstanbul-TurkeyDepartment of Cardiology, Faculty of Medicine, Hitit University; Çorum-TurkeyDepartment of Cardiology, Koşuyolu Kartal Heart Training and Research Hospital; İstanbul-TurkeyDepartment of Cardiology, Koşuyolu Kartal Heart Training and Research Hospital; İstanbul-TurkeyMitral paravalvular leaks (PVLs) commonly occur in patients with prosthetic valves. Paravalvular defects may be clinically inconsequential and may aggravate hemolysis or cause heart failure through regurgitation. Accordingly, patients may eventually require intervention such as redo surgery or a transcatheter closure of the defects. The introduction of purpose-specific closure devices and new steerable catheters has opened a new frontier for the transcatheter PVL closure. This mode of treatment is an initial therapy in most centers with experienced structural heart team. However, head-to-head data comparing two treatment modalities (surgery and transcatheter closure) are limited, and the world-wide experience is based on nonrandomized studies. Multimodality imaging, including three-dimensional transesophageal echocardiography, facilitates the delineation of mitral PVLs and provides essential data that aids the communication between the members of the structural heart team. In the near future, the success of interventional therapies will most probably increase in patients with mitral PVLs with the introduction of hybrid imaging modalities (echocardiography, cardiac computed tomography, and fluoroscopy). In conclusion, this paper summarizes the etiopathogenesis, clinical characteristics, diagnosis, and treatment of mitral PVLs.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=anatoljcardiol&un=AJC-10018mitral valveechocardiographytranscatheter closurecardiac surgery |
| spellingShingle | Mustafa Ozan Gürsoy Ahmet Güner Macit Kalçık Emrah Bayam Mehmet Özkan A comprehensive review of the diagnosis and management of mitral paravalvular leakage Anatolian Journal of Cardiology mitral valve echocardiography transcatheter closure cardiac surgery |
| title | A comprehensive review of the diagnosis and management of mitral paravalvular leakage |
| title_full | A comprehensive review of the diagnosis and management of mitral paravalvular leakage |
| title_fullStr | A comprehensive review of the diagnosis and management of mitral paravalvular leakage |
| title_full_unstemmed | A comprehensive review of the diagnosis and management of mitral paravalvular leakage |
| title_short | A comprehensive review of the diagnosis and management of mitral paravalvular leakage |
| title_sort | comprehensive review of the diagnosis and management of mitral paravalvular leakage |
| topic | mitral valve echocardiography transcatheter closure cardiac surgery |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=anatoljcardiol&un=AJC-10018 |
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