Polyphenol-rich blue honeysuckle extract alleviates silica particle-induced inflammatory responses and macrophage apoptosis via NRF2/HO-1 and MAPK signaling

Polyphenol-rich blue honeysuckle extract alleviates silica particle-induced inflammatory responses and macrophage apoptosis via NRF2/HO-1 and MAPK signaling

The blue honeysuckle is a rich source of bioactive compounds. In this study, we obtained a polyphenol-rich blue honeysuckle extract (BHE) and found that cyanidin 3-glucoside and chlorogenic acid accounted for most of its phenolic content. Administration of BHE to mice alleviated silica particle (SP)...

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Bibliographic Details
Main Authors: Jin Zhao, Yang Lin, Yingbo Zhao, Yuehua Wang, Chong Ning, Yan Ma, Xianjun Meng
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:Journal of Functional Foods
Subjects:
Blue honeysuckle
Polyphenol
Lung inflammation
Macrophage
Inflammatory cytokine
Antioxidant
Online Access:http://www.sciencedirect.com/science/article/pii/S175646461830241X

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