Association of CCR2-CCR5 haplotypes and CCL3L1 copy number with Kawasaki Disease, coronary artery lesions, and IVIG responses in Japanese children.

Association of CCR2-CCR5 haplotypes and CCL3L1 copy number with Kawasaki Disease, coronary artery lesions, and IVIG responses in Japanese children.

The etiology of Kawasaki Disease (KD) is enigmatic, although an infectious cause is suspected. Polymorphisms in CC chemokine receptor 5 (CCR5) and/or its potent ligand CCL3L1 influence KD susceptibility in US, European and Korean populations. However, the influence of these variations on KD suscepti...

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Bibliographic Details
Main Authors: Manju Mamtani, Tomoyo Matsubara, Chisato Shimizu, Susumu Furukawa, Teiji Akagi, Yoshihiro Onouchi, Akira Hata, Akihiro Fujino, Weijing He, Sunil K Ahuja, Jane C Burns
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2898815?pdf=render

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