Ketamine ameliorates hypoxia-induced endothelial injury in human umbilical vein endothelial cells

OBJECTIVES: Hypoxia leads to endothelial cell inflammation, apoptosis, and damage, which plays an important role in the complications associated with ischemic cardiovascular disease. As an oxidoreductase, p66Shc plays an important role in the regulation of reactive oxygen species (ROS) production an...

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Bibliographic Details
Main Authors: Xiaohui Zhou, Jing Liu, Siyi Yang, Yanguang Su, Zhipeng Meng, Yuqin Hu
Format: Article
Language:English
Published: Elsevier España
Series:Clinics
Subjects:
Online Access:http://www.scielo.br/pdf/clin/v75/1807-5932-clin-75-e1865.pdf