A Diarrhoeic Dog with Clinical and Histopathologic Signs of ICH (Infectious Canine Hepatitis)

A 3-month-old male German shepherd dog was referred with depression, vomition, hemorrhagic diarrhea, abdominal pain, anorexia and dehydration. The affected dog did not have any history of vaccination. Despite treatment, the animal died within 2 days after the onset of clinical signs. Gross examinati...

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Main Authors: Bahman Mosallanejad, Saleh Esmailzadeh, Reza Avizeh
Format: Article
Language:English
Published: Ferdowsi University of Mashhad 2010-09-01
Series:The Iranian Journal of Veterinary Science and Technology
Subjects:
Online Access:https://ijvst.um.ac.ir/article_25634_fffb3f18d09876a86da354b8a03d47b3.pdf
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author Bahman Mosallanejad
Saleh Esmailzadeh
Reza Avizeh
author_facet Bahman Mosallanejad
Saleh Esmailzadeh
Reza Avizeh
author_sort Bahman Mosallanejad
collection DOAJ
description A 3-month-old male German shepherd dog was referred with depression, vomition, hemorrhagic diarrhea, abdominal pain, anorexia and dehydration. The affected dog did not have any history of vaccination. Despite treatment, the animal died within 2 days after the onset of clinical signs. Gross examination of tissues showed hemorrhages (ecchymoses) in the mucosa of the digestive tract. The liver was congested and slightly enlarged. The gall bladder wall was edematous. The spleen and lymph nodes were also edematous and congested. Light microscopic examination of tissues showed numerous large, basophilic intranuclear inclusion bodies within the hepatcytes and endothelial cells adjacent to the necrotic regions. A large area of hepatic necrosis, severe congestion of sinusoids accompanied by a mild mixed infiltration of inflammatory cells, were evident particularly in the periportal region. Fecal sample was examined for differential diagnosis of other viral, bacterial and parasitic diseases. Based on histopathological findings, Infectious canine Hepatitis (ICH) was suspected as the cause of death.
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spelling doaj.art-344c103957dc4f83b5580f6509fe7cc82022-12-22T02:20:38ZengFerdowsi University of MashhadThe Iranian Journal of Veterinary Science and Technology2008-465X2423-63062010-09-012212312810.22067/veterinary.v2i2.837725634A Diarrhoeic Dog with Clinical and Histopathologic Signs of ICH (Infectious Canine Hepatitis)Bahman Mosallanejad0Saleh Esmailzadeh1Reza Avizeh2Shahid Chamran University of AhvazShahid Chamran University of AhvazShahid Chamran University of AhvazA 3-month-old male German shepherd dog was referred with depression, vomition, hemorrhagic diarrhea, abdominal pain, anorexia and dehydration. The affected dog did not have any history of vaccination. Despite treatment, the animal died within 2 days after the onset of clinical signs. Gross examination of tissues showed hemorrhages (ecchymoses) in the mucosa of the digestive tract. The liver was congested and slightly enlarged. The gall bladder wall was edematous. The spleen and lymph nodes were also edematous and congested. Light microscopic examination of tissues showed numerous large, basophilic intranuclear inclusion bodies within the hepatcytes and endothelial cells adjacent to the necrotic regions. A large area of hepatic necrosis, severe congestion of sinusoids accompanied by a mild mixed infiltration of inflammatory cells, were evident particularly in the periportal region. Fecal sample was examined for differential diagnosis of other viral, bacterial and parasitic diseases. Based on histopathological findings, Infectious canine Hepatitis (ICH) was suspected as the cause of death.https://ijvst.um.ac.ir/article_25634_fffb3f18d09876a86da354b8a03d47b3.pdfdoginfectious canine hepatitispathology
spellingShingle Bahman Mosallanejad
Saleh Esmailzadeh
Reza Avizeh
A Diarrhoeic Dog with Clinical and Histopathologic Signs of ICH (Infectious Canine Hepatitis)
The Iranian Journal of Veterinary Science and Technology
dog
infectious canine hepatitis
pathology
title A Diarrhoeic Dog with Clinical and Histopathologic Signs of ICH (Infectious Canine Hepatitis)
title_full A Diarrhoeic Dog with Clinical and Histopathologic Signs of ICH (Infectious Canine Hepatitis)
title_fullStr A Diarrhoeic Dog with Clinical and Histopathologic Signs of ICH (Infectious Canine Hepatitis)
title_full_unstemmed A Diarrhoeic Dog with Clinical and Histopathologic Signs of ICH (Infectious Canine Hepatitis)
title_short A Diarrhoeic Dog with Clinical and Histopathologic Signs of ICH (Infectious Canine Hepatitis)
title_sort diarrhoeic dog with clinical and histopathologic signs of ich infectious canine hepatitis
topic dog
infectious canine hepatitis
pathology
url https://ijvst.um.ac.ir/article_25634_fffb3f18d09876a86da354b8a03d47b3.pdf
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