Formation mechanism of thermally controlled pH gradients

Cells use pH gradients to drive the synthesis of adenosine triphosphate (ATP), but the physicochemical mechanisms that can produce pH gradients in non-equilibrium settings are poorly understood. The authors here theoretically and experimentally investigate the formation of a pH gradient in an acid-b...

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Bibliographic Details
Main Authors: Thomas Matreux, Bernhard Altaner, Johannes Raith, Dieter Braun, Christof B. Mast, Ulrich Gerland
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Communications Physics
Online Access:https://doi.org/10.1038/s42005-023-01126-y
Description
Summary:Cells use pH gradients to drive the synthesis of adenosine triphosphate (ATP), but the physicochemical mechanisms that can produce pH gradients in non-equilibrium settings are poorly understood. The authors here theoretically and experimentally investigate the formation of a pH gradient in an acid-base reaction system, driven by a heat flow, providing insights on how crude non-equilibrium systems can feed chemical gradients exploitable by life.
ISSN:2399-3650