Validation of the X-ray microtomography in the assessment of duodenal morphometry and surface area in celiac disease

Validation of the X-ray microtomography in the assessment of duodenal morphometry and surface area in celiac disease

BackgroundDuodenal histology remains the diagnostic reference standard in celiac disease. However, traditional methods have suboptimal sensitivity and reproducibility for early mucosal changes and research purposes. We validated a recently introduced micro-CT imaging method for an accurate digital e...

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Bibliographic Details
Main Authors: Johannes Virta, Markus Hannula, Katri Lindfors, Ilmari Tamminen, Juha Taavela, Heini Huhtala, Katri Kaukinen, Päivi Saavalainen, Jari Hyttinen, Kalle Kurppa
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
celiac disease
biopsies
histology
diagnosis
micro-CT
imaging
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.945197/full

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