Fast and convenient synthesis of new symmetric pyrano[2,3-d:6,5-d']dipyrimidinones by an organocatalyzed annulation reaction

A fast and facile one-pot procedure for the preparation of symmetric 5-Aryloyl-1,9-dimethyl-5,9-dihydro-2H-pyrano[2,3-d:6,5-d']dipyrimidine-2,4,6,8(1H,3H,7H)-tetraone derivatives by two-component reaction of N-methylbarbituric acid and arylglyoxalmonohydrates catalyzed by DABCO in ethanol at 50...

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Main Authors: Mehdi Rimaz, Hossein Mousavi, Mojgan Behnam, Leila Sarvari, Behzad Khalili
Format: Article
Language:English
Published: Growing Science 2017-02-01
Series:Current Chemistry Letters
Subjects:
Online Access:http://www.growingscience.com/ccl/Vol6/ccl_2016_21.pdf
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author Mehdi Rimaz
Hossein Mousavi
Mojgan Behnam
Leila Sarvari
Behzad Khalili
author_facet Mehdi Rimaz
Hossein Mousavi
Mojgan Behnam
Leila Sarvari
Behzad Khalili
author_sort Mehdi Rimaz
collection DOAJ
description A fast and facile one-pot procedure for the preparation of symmetric 5-Aryloyl-1,9-dimethyl-5,9-dihydro-2H-pyrano[2,3-d:6,5-d']dipyrimidine-2,4,6,8(1H,3H,7H)-tetraone derivatives by two-component reaction of N-methylbarbituric acid and arylglyoxalmonohydrates catalyzed by DABCO in ethanol at 50 ºC is described. This protocol has the advantages of environmental friendless, very simple operation, high regio- and chemoselectivity and moderate to excellent yields.
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spelling doaj.art-345ccef695e048259eea05c4020cc9892022-12-21T23:37:58ZengGrowing ScienceCurrent Chemistry Letters1927-72961927-730X2017-02-0162556810.5267/j.ccl.2016.12.001Fast and convenient synthesis of new symmetric pyrano[2,3-d:6,5-d']dipyrimidinones by an organocatalyzed annulation reactionMehdi RimazHossein MousaviMojgan BehnamLeila SarvariBehzad Khalili A fast and facile one-pot procedure for the preparation of symmetric 5-Aryloyl-1,9-dimethyl-5,9-dihydro-2H-pyrano[2,3-d:6,5-d']dipyrimidine-2,4,6,8(1H,3H,7H)-tetraone derivatives by two-component reaction of N-methylbarbituric acid and arylglyoxalmonohydrates catalyzed by DABCO in ethanol at 50 ºC is described. This protocol has the advantages of environmental friendless, very simple operation, high regio- and chemoselectivity and moderate to excellent yields.http://www.growingscience.com/ccl/Vol6/ccl_2016_21.pdfPyranodipyrimidinonesDABCOOne-potArylglyoxalmonohydrate
spellingShingle Mehdi Rimaz
Hossein Mousavi
Mojgan Behnam
Leila Sarvari
Behzad Khalili
Fast and convenient synthesis of new symmetric pyrano[2,3-d:6,5-d']dipyrimidinones by an organocatalyzed annulation reaction
Current Chemistry Letters
Pyranodipyrimidinones
DABCO
One-pot
Arylglyoxalmonohydrate
title Fast and convenient synthesis of new symmetric pyrano[2,3-d:6,5-d']dipyrimidinones by an organocatalyzed annulation reaction
title_full Fast and convenient synthesis of new symmetric pyrano[2,3-d:6,5-d']dipyrimidinones by an organocatalyzed annulation reaction
title_fullStr Fast and convenient synthesis of new symmetric pyrano[2,3-d:6,5-d']dipyrimidinones by an organocatalyzed annulation reaction
title_full_unstemmed Fast and convenient synthesis of new symmetric pyrano[2,3-d:6,5-d']dipyrimidinones by an organocatalyzed annulation reaction
title_short Fast and convenient synthesis of new symmetric pyrano[2,3-d:6,5-d']dipyrimidinones by an organocatalyzed annulation reaction
title_sort fast and convenient synthesis of new symmetric pyrano 2 3 d 6 5 d dipyrimidinones by an organocatalyzed annulation reaction
topic Pyranodipyrimidinones
DABCO
One-pot
Arylglyoxalmonohydrate
url http://www.growingscience.com/ccl/Vol6/ccl_2016_21.pdf
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