Stroke recurrence in the different subtypes of ischemic stroke. The importance of the intracranial disease
ABSTRACT The aim of the study was to analyze the long-term recurrence rate in patients with a first-ever ischemic stroke secondary to intracranial large artery atherosclerosis (LAA) in a Brazilian population. Methods: All stroke patients admitted to the hospital between October 2012 and September 20...
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| Format: | Article |
| Language: | English |
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Academia Brasileira de Neurologia (ABNEURO)
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| Series: | Arquivos de Neuro-Psiquiatria |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2018001000649&lng=en&tlng=en |
| _version_ | 1818274901656600576 |
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| author | Marcos C Lange Gustavo Ribas Valeria Scavasine Renata Dal-Prá Ducci Danielle C. Mendes Viviane de Hiroki Flumignan Zétola Norberto Cabral Tatjana Rundek |
| author_facet | Marcos C Lange Gustavo Ribas Valeria Scavasine Renata Dal-Prá Ducci Danielle C. Mendes Viviane de Hiroki Flumignan Zétola Norberto Cabral Tatjana Rundek |
| author_sort | Marcos C Lange |
| collection | DOAJ |
| description | ABSTRACT The aim of the study was to analyze the long-term recurrence rate in patients with a first-ever ischemic stroke secondary to intracranial large artery atherosclerosis (LAA) in a Brazilian population. Methods: All stroke patients admitted to the hospital between October 2012 and September 2015 were evaluated. The stroke mechanism subtypes were classified as cardioembolism, LAA, small-vessel occlusion, other determined etiologies, and stroke of undetermined etiology. Results: The 359 first-ever ischemic stroke patients were followed up for a mean time of 21.6 ± 15.1 months. The LAA intracranial (38.9%) and extracranial (24.6%) stroke patients presented with a higher stroke recurrence. Intracranial LAA [HR, 10.2 (3.6–29.1); p < 0.001] and extracranial LAA [HR, 5.05 (1.79–14.2); p = 0.002] were the only conditions to show positive correlation with the recurrence rate, after adjusting for risk factors, thrombolysis, and National Institutes of Health Stroke Scale score at admission. Conclusion: Intracranial LAA presents a higher incidence of recurrence of ischemic stroke when compared with other etiologies in a Southern Brazilian population. |
| first_indexed | 2024-12-12T22:21:13Z |
| format | Article |
| id | doaj.art-345ecfc1e3794d20a6f7e3347031c21c |
| institution | Directory Open Access Journal |
| issn | 1678-4227 |
| language | English |
| last_indexed | 2024-12-12T22:21:13Z |
| publisher | Academia Brasileira de Neurologia (ABNEURO) |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj.art-345ecfc1e3794d20a6f7e3347031c21c2022-12-22T00:09:54ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria1678-4227761064965310.1590/0004-282x20180095S0004-282X2018001000649Stroke recurrence in the different subtypes of ischemic stroke. The importance of the intracranial diseaseMarcos C LangeGustavo RibasValeria ScavasineRenata Dal-Prá DucciDanielle C. MendesViviane de Hiroki Flumignan ZétolaNorberto CabralTatjana RundekABSTRACT The aim of the study was to analyze the long-term recurrence rate in patients with a first-ever ischemic stroke secondary to intracranial large artery atherosclerosis (LAA) in a Brazilian population. Methods: All stroke patients admitted to the hospital between October 2012 and September 2015 were evaluated. The stroke mechanism subtypes were classified as cardioembolism, LAA, small-vessel occlusion, other determined etiologies, and stroke of undetermined etiology. Results: The 359 first-ever ischemic stroke patients were followed up for a mean time of 21.6 ± 15.1 months. The LAA intracranial (38.9%) and extracranial (24.6%) stroke patients presented with a higher stroke recurrence. Intracranial LAA [HR, 10.2 (3.6–29.1); p < 0.001] and extracranial LAA [HR, 5.05 (1.79–14.2); p = 0.002] were the only conditions to show positive correlation with the recurrence rate, after adjusting for risk factors, thrombolysis, and National Institutes of Health Stroke Scale score at admission. Conclusion: Intracranial LAA presents a higher incidence of recurrence of ischemic stroke when compared with other etiologies in a Southern Brazilian population.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2018001000649&lng=en&tlng=enstrokeatherosclerosisrecurrencerisk factors |
| spellingShingle | Marcos C Lange Gustavo Ribas Valeria Scavasine Renata Dal-Prá Ducci Danielle C. Mendes Viviane de Hiroki Flumignan Zétola Norberto Cabral Tatjana Rundek Stroke recurrence in the different subtypes of ischemic stroke. The importance of the intracranial disease Arquivos de Neuro-Psiquiatria stroke atherosclerosis recurrence risk factors |
| title | Stroke recurrence in the different subtypes of ischemic stroke. The importance of the intracranial disease |
| title_full | Stroke recurrence in the different subtypes of ischemic stroke. The importance of the intracranial disease |
| title_fullStr | Stroke recurrence in the different subtypes of ischemic stroke. The importance of the intracranial disease |
| title_full_unstemmed | Stroke recurrence in the different subtypes of ischemic stroke. The importance of the intracranial disease |
| title_short | Stroke recurrence in the different subtypes of ischemic stroke. The importance of the intracranial disease |
| title_sort | stroke recurrence in the different subtypes of ischemic stroke the importance of the intracranial disease |
| topic | stroke atherosclerosis recurrence risk factors |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2018001000649&lng=en&tlng=en |
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