IRAK2, an IL1R/TLR Immune Mediator, Enhances Radiosensitivity via Modulating Caspase 8/3-Mediated Apoptosis in Oral Squamous Cell Carcinoma

IRAK2, an IL1R/TLR Immune Mediator, Enhances Radiosensitivity via Modulating Caspase 8/3-Mediated Apoptosis in Oral Squamous Cell Carcinoma

Predicting and overcoming radioresistance are crucial in radiation oncology, including in managing oral squamous cell carcinoma (OSCC). First, we used RNA-sequence to compare expression profiles of parent OML1 and radioresistant OML1-R OSCC cells in order to select candidate genes responsible for ra...

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Bibliographic Details
Main Authors: Chih-Chia Yu, Michael W.Y. Chan, Hon-Yi Lin, Wen-Yen Chiou, Ru-Inn Lin, Chien-An Chen, Moon-Sing Lee, Chen-Lin Chi, Liang-Cheng Chen, Li-Wen Huang, Chia-Hui Chew, Feng-Chun Hsu, Hsuan-Ju Yang, Shih-Kai Hung
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Oncology
Subjects:
IRAK2
radioresistant
apoptosis
radiosensitization
oral squamous cell carcinoma
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.647175/full

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