Intervertebral discs degeneration and methods of its biological correction

Human physical possibilities limitation caused by intervertebral discs degenerative diseases is a serious medical and social problem in our time. Main signs of intervertebral discs degenerative diseases — cells death, proteoglycane and collagen synthesis decrease. Intervertebral discs deg...

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Main Authors: I. G. Vasilyeva, M. V. Khyzhnyak, I. N. Shuba, Yu. G. Gafiychuk
Format: Article
Language:English
Published: Romodanov Neurosurgery Institute 2010-03-01
Series:Ukrainian Neurosurgical Journal
Online Access:https://theunj.org/article/view/88759
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author I. G. Vasilyeva
M. V. Khyzhnyak
I. N. Shuba
Yu. G. Gafiychuk
author_facet I. G. Vasilyeva
M. V. Khyzhnyak
I. N. Shuba
Yu. G. Gafiychuk
author_sort I. G. Vasilyeva
collection DOAJ
description Human physical possibilities limitation caused by intervertebral discs degenerative diseases is a serious medical and social problem in our time. Main signs of intervertebral discs degenerative diseases — cells death, proteoglycane and collagen synthesis decrease. Intervertebral discs degeneration is frequent cause of painful syndrome forming. Today therapy is directed not only on painful syndrome elimination but also on dick’s functions renewing. Modern technologies are frequently based on biological materials using. Injections of proteins activators, biomaterials, different cell types or cell complexes and extracellular matrix, genetically modified cells, and in vitro constructed tissue are used for intravertebral disc regeneration activation. Using one or another therapeutic tactic sufficiently depends on degenerative state expressivity, taking into account the procedure safety.
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spelling doaj.art-346506c2c6b94a57b2e51275317e31a62024-02-03T08:07:44ZengRomodanov Neurosurgery InstituteUkrainian Neurosurgical Journal2663-90842663-90922010-03-011162310.25305/unj.88759Intervertebral discs degeneration and methods of its biological correctionI. G. Vasilyeva0M. V. Khyzhnyak1I. N. Shuba2Yu. G. Gafiychuk3Romodanov Neurosurgery Institute, Kiev, UkraineRomodanov Neurosurgery Institute, Kiev, UkraineRomodanov Neurosurgery Institute, Kiev, UkraineRomodanov Neurosurgery Institute, Kiev, Ukraine Human physical possibilities limitation caused by intervertebral discs degenerative diseases is a serious medical and social problem in our time. Main signs of intervertebral discs degenerative diseases — cells death, proteoglycane and collagen synthesis decrease. Intervertebral discs degeneration is frequent cause of painful syndrome forming. Today therapy is directed not only on painful syndrome elimination but also on dick’s functions renewing. Modern technologies are frequently based on biological materials using. Injections of proteins activators, biomaterials, different cell types or cell complexes and extracellular matrix, genetically modified cells, and in vitro constructed tissue are used for intravertebral disc regeneration activation. Using one or another therapeutic tactic sufficiently depends on degenerative state expressivity, taking into account the procedure safety.https://theunj.org/article/view/88759
spellingShingle I. G. Vasilyeva
M. V. Khyzhnyak
I. N. Shuba
Yu. G. Gafiychuk
Intervertebral discs degeneration and methods of its biological correction
Ukrainian Neurosurgical Journal
title Intervertebral discs degeneration and methods of its biological correction
title_full Intervertebral discs degeneration and methods of its biological correction
title_fullStr Intervertebral discs degeneration and methods of its biological correction
title_full_unstemmed Intervertebral discs degeneration and methods of its biological correction
title_short Intervertebral discs degeneration and methods of its biological correction
title_sort intervertebral discs degeneration and methods of its biological correction
url https://theunj.org/article/view/88759
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