Intervertebral discs degeneration and methods of its biological correction
Human physical possibilities limitation caused by intervertebral discs degenerative diseases is a serious medical and social problem in our time. Main signs of intervertebral discs degenerative diseases — cells death, proteoglycane and collagen synthesis decrease. Intervertebral discs deg...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Romodanov Neurosurgery Institute
2010-03-01
|
Series: | Ukrainian Neurosurgical Journal |
Online Access: | https://theunj.org/article/view/88759 |
_version_ | 1797327943959052288 |
---|---|
author | I. G. Vasilyeva M. V. Khyzhnyak I. N. Shuba Yu. G. Gafiychuk |
author_facet | I. G. Vasilyeva M. V. Khyzhnyak I. N. Shuba Yu. G. Gafiychuk |
author_sort | I. G. Vasilyeva |
collection | DOAJ |
description |
Human physical possibilities limitation caused by intervertebral discs degenerative diseases is a serious medical and social problem in our time. Main signs of intervertebral discs degenerative diseases — cells death, proteoglycane and collagen synthesis decrease. Intervertebral discs degeneration is frequent cause of painful syndrome forming. Today therapy is directed not only on painful syndrome elimination but also on dick’s functions renewing. Modern technologies are frequently based on biological materials using. Injections of proteins activators, biomaterials, different cell types or cell complexes and extracellular matrix, genetically modified cells, and in vitro constructed tissue are used for intravertebral disc regeneration activation. Using one or another therapeutic tactic sufficiently depends on degenerative state expressivity, taking into account the procedure safety. |
first_indexed | 2024-03-08T06:45:02Z |
format | Article |
id | doaj.art-346506c2c6b94a57b2e51275317e31a6 |
institution | Directory Open Access Journal |
issn | 2663-9084 2663-9092 |
language | English |
last_indexed | 2024-03-08T06:45:02Z |
publishDate | 2010-03-01 |
publisher | Romodanov Neurosurgery Institute |
record_format | Article |
series | Ukrainian Neurosurgical Journal |
spelling | doaj.art-346506c2c6b94a57b2e51275317e31a62024-02-03T08:07:44ZengRomodanov Neurosurgery InstituteUkrainian Neurosurgical Journal2663-90842663-90922010-03-011162310.25305/unj.88759Intervertebral discs degeneration and methods of its biological correctionI. G. Vasilyeva0M. V. Khyzhnyak1I. N. Shuba2Yu. G. Gafiychuk3Romodanov Neurosurgery Institute, Kiev, UkraineRomodanov Neurosurgery Institute, Kiev, UkraineRomodanov Neurosurgery Institute, Kiev, UkraineRomodanov Neurosurgery Institute, Kiev, Ukraine Human physical possibilities limitation caused by intervertebral discs degenerative diseases is a serious medical and social problem in our time. Main signs of intervertebral discs degenerative diseases — cells death, proteoglycane and collagen synthesis decrease. Intervertebral discs degeneration is frequent cause of painful syndrome forming. Today therapy is directed not only on painful syndrome elimination but also on dick’s functions renewing. Modern technologies are frequently based on biological materials using. Injections of proteins activators, biomaterials, different cell types or cell complexes and extracellular matrix, genetically modified cells, and in vitro constructed tissue are used for intravertebral disc regeneration activation. Using one or another therapeutic tactic sufficiently depends on degenerative state expressivity, taking into account the procedure safety.https://theunj.org/article/view/88759 |
spellingShingle | I. G. Vasilyeva M. V. Khyzhnyak I. N. Shuba Yu. G. Gafiychuk Intervertebral discs degeneration and methods of its biological correction Ukrainian Neurosurgical Journal |
title | Intervertebral discs degeneration and methods of its biological correction |
title_full | Intervertebral discs degeneration and methods of its biological correction |
title_fullStr | Intervertebral discs degeneration and methods of its biological correction |
title_full_unstemmed | Intervertebral discs degeneration and methods of its biological correction |
title_short | Intervertebral discs degeneration and methods of its biological correction |
title_sort | intervertebral discs degeneration and methods of its biological correction |
url | https://theunj.org/article/view/88759 |
work_keys_str_mv | AT igvasilyeva intervertebraldiscsdegenerationandmethodsofitsbiologicalcorrection AT mvkhyzhnyak intervertebraldiscsdegenerationandmethodsofitsbiologicalcorrection AT inshuba intervertebraldiscsdegenerationandmethodsofitsbiologicalcorrection AT yuggafiychuk intervertebraldiscsdegenerationandmethodsofitsbiologicalcorrection |