Effects of Adolescent THC Exposure on the Prefrontal GABAergic System: Implications for Schizophrenia-Related Psychopathology

Effects of Adolescent THC Exposure on the Prefrontal GABAergic System: Implications for Schizophrenia-Related Psychopathology

Marijuana is the most commonly used drug of abuse among adolescents. Considerable clinical evidence supports the hypothesis that adolescent neurodevelopmental exposure to high levels of the principal psychoactive component in marijuana, -delta-9-tetrahydrocanabinol (THC), is associated with a high r...

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Bibliographic Details
Main Authors: Justine Renard, Walter J. Rushlow, Steven R. Laviolette
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Psychiatry
Subjects:
GABAergic transmission
adolescence
cannabis
prefrontal cortex (PFC)
psychiatric diseases
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2018.00281/full

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