POST-DISCHARGE FOLLOW-UP WITH QUALITY OF LIFE ASSESSMENT IN COVID 19 PATIENTS ADMITTED DURING THE COVID 19 PANDEMIC

Intro: Patients affected with COVID-19 have been reported to have persistent symptoms even months after the acute episode, most commonly fatigue, breathlessness, and symptoms of anxiety and depression. These residual symptoms have been shown to compromise the quality of life and lead to significant...

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Main Authors: B. Syed, M. Ahsan, I. Memon
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:International Journal of Infectious Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971223004290
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author B. Syed
M. Ahsan
I. Memon
author_facet B. Syed
M. Ahsan
I. Memon
author_sort B. Syed
collection DOAJ
description Intro: Patients affected with COVID-19 have been reported to have persistent symptoms even months after the acute episode, most commonly fatigue, breathlessness, and symptoms of anxiety and depression. These residual symptoms have been shown to compromise the quality of life and lead to significant impairment in both the mental and physical health of these patients. Methods: A prospective observational cohort study was carried out and patients were followed for a month after discharge. Residual symptoms were noted, quality of life (QoL) assessment was done using EQ-5D-5L, and anxiety/depression was evaluated using WHO-SRQ 20 scores. Appropriate statistical tests were applied to compare improvement in QoL and residual symptoms between first and the last visit. Findings: A total of 110 patients were included. Mean age of the patients was 53.7 (SD+/- 13) years. Most common symptoms at 1st follow up were shortness of breath (66%) and fatigue (65%) which reduced in frequency on the last visit to (43%) and (46%) respectively. Significant improvement was seen in SpO2 levels recorded at both visits (p=0.000). An overall improvement in QoL was seen (p=0.000). WHO-SRQ 20 score above 8 was noted in 20% patients and mean score was 5.91. On further categorization into mild, moderate, severe and critical disease on admission, patients showed improvement in symptoms at four weeks irrespective of categories. For QoL assessment, mean utility score showed improvement in all disease categories on the 2nd visit except for patients with mild disease on admission. Conclusion: Our study showed a significant improvement in residual symptoms and overall quality of life when followed over a period of time in majority of the patients. Symptoms of anxiety and depression were also not frequent. However, our findings emphasize the need of a multidisciplinary approach towards rehabilitation of COVID-19 patients for earlier improvement in their quality of life.
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spelling doaj.art-34672e1b079442f2a5057a2a59484b992023-05-18T04:38:57ZengElsevierInternational Journal of Infectious Diseases1201-97122023-05-01130S121S122POST-DISCHARGE FOLLOW-UP WITH QUALITY OF LIFE ASSESSMENT IN COVID 19 PATIENTS ADMITTED DURING THE COVID 19 PANDEMICB. Syed0M. Ahsan1I. Memon2Sindh Infectious Diseases Hospital and Research Center, Infectious Diseases, Karachi, PakistanSindh Infectious Diseases Hospital and Research Center, Infectious Diseases, Karachi, PakistanSindh Infectious Diseases Hospital and Research Center, Infectious Diseases, Karachi, PakistanIntro: Patients affected with COVID-19 have been reported to have persistent symptoms even months after the acute episode, most commonly fatigue, breathlessness, and symptoms of anxiety and depression. These residual symptoms have been shown to compromise the quality of life and lead to significant impairment in both the mental and physical health of these patients. Methods: A prospective observational cohort study was carried out and patients were followed for a month after discharge. Residual symptoms were noted, quality of life (QoL) assessment was done using EQ-5D-5L, and anxiety/depression was evaluated using WHO-SRQ 20 scores. Appropriate statistical tests were applied to compare improvement in QoL and residual symptoms between first and the last visit. Findings: A total of 110 patients were included. Mean age of the patients was 53.7 (SD+/- 13) years. Most common symptoms at 1st follow up were shortness of breath (66%) and fatigue (65%) which reduced in frequency on the last visit to (43%) and (46%) respectively. Significant improvement was seen in SpO2 levels recorded at both visits (p=0.000). An overall improvement in QoL was seen (p=0.000). WHO-SRQ 20 score above 8 was noted in 20% patients and mean score was 5.91. On further categorization into mild, moderate, severe and critical disease on admission, patients showed improvement in symptoms at four weeks irrespective of categories. For QoL assessment, mean utility score showed improvement in all disease categories on the 2nd visit except for patients with mild disease on admission. Conclusion: Our study showed a significant improvement in residual symptoms and overall quality of life when followed over a period of time in majority of the patients. Symptoms of anxiety and depression were also not frequent. However, our findings emphasize the need of a multidisciplinary approach towards rehabilitation of COVID-19 patients for earlier improvement in their quality of life.http://www.sciencedirect.com/science/article/pii/S1201971223004290
spellingShingle B. Syed
M. Ahsan
I. Memon
POST-DISCHARGE FOLLOW-UP WITH QUALITY OF LIFE ASSESSMENT IN COVID 19 PATIENTS ADMITTED DURING THE COVID 19 PANDEMIC
International Journal of Infectious Diseases
title POST-DISCHARGE FOLLOW-UP WITH QUALITY OF LIFE ASSESSMENT IN COVID 19 PATIENTS ADMITTED DURING THE COVID 19 PANDEMIC
title_full POST-DISCHARGE FOLLOW-UP WITH QUALITY OF LIFE ASSESSMENT IN COVID 19 PATIENTS ADMITTED DURING THE COVID 19 PANDEMIC
title_fullStr POST-DISCHARGE FOLLOW-UP WITH QUALITY OF LIFE ASSESSMENT IN COVID 19 PATIENTS ADMITTED DURING THE COVID 19 PANDEMIC
title_full_unstemmed POST-DISCHARGE FOLLOW-UP WITH QUALITY OF LIFE ASSESSMENT IN COVID 19 PATIENTS ADMITTED DURING THE COVID 19 PANDEMIC
title_short POST-DISCHARGE FOLLOW-UP WITH QUALITY OF LIFE ASSESSMENT IN COVID 19 PATIENTS ADMITTED DURING THE COVID 19 PANDEMIC
title_sort post discharge follow up with quality of life assessment in covid 19 patients admitted during the covid 19 pandemic
url http://www.sciencedirect.com/science/article/pii/S1201971223004290
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