Vitamin C-Catalyzed Hantzsch reaction under microwave condition: A greener access to 1,4-Dihydropyridines

A cost effective, operationally simple and environmentally benign one-pot access to 1,4-dihydropyridine (DHP) derivatives was achieved through the successful utilization of vitamin C as catalyst under microwave irradiation. The applicability of this method was fairly demonstrated through implementat...

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Main Authors: Devalina Ray, Ram Naresh Yadav, Bimal Krishna Banik
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Results in Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715622000492
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author Devalina Ray
Ram Naresh Yadav
Bimal Krishna Banik
author_facet Devalina Ray
Ram Naresh Yadav
Bimal Krishna Banik
author_sort Devalina Ray
collection DOAJ
description A cost effective, operationally simple and environmentally benign one-pot access to 1,4-dihydropyridine (DHP) derivatives was achieved through the successful utilization of vitamin C as catalyst under microwave irradiation. The applicability of this method was fairly demonstrated through implementation of reaction conditions on diversified substrates. A plausible mechanistic interpretation for this reaction has been outlined based on Hantzsch reaction.
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spelling doaj.art-3467619e83b942e68b49027930c1a7ad2022-12-22T03:00:21ZengElsevierResults in Chemistry2211-71562022-01-014100330Vitamin C-Catalyzed Hantzsch reaction under microwave condition: A greener access to 1,4-DihydropyridinesDevalina Ray0Ram Naresh Yadav1Bimal Krishna Banik2Amity Institute of Biotechnology, Amity University, Sector 125, Noida 201313, Uttar Pradesh, IndiaDepartment of Chemistry, Faculty of Engineering and Technology, Veer Bahadur Singh Purvanchal University, Jaunpur-222 003, Uttar Pradesh, IndiaDepartment of Chemistry, University of Texas-Pan American, 1201 W. University Dr., Edinburg, TX 78539, USA; Department of Mathematics and Natural Sciences, College of Sciences and Human Studies, Prince Mohammad Bin Fahd University, Al Khobar, Kingdom of Saudi Arabia; Corresponding author.A cost effective, operationally simple and environmentally benign one-pot access to 1,4-dihydropyridine (DHP) derivatives was achieved through the successful utilization of vitamin C as catalyst under microwave irradiation. The applicability of this method was fairly demonstrated through implementation of reaction conditions on diversified substrates. A plausible mechanistic interpretation for this reaction has been outlined based on Hantzsch reaction.http://www.sciencedirect.com/science/article/pii/S221171562200049214-Dihydropyridine (DHP)Vitamin CMicrowave synthesisHantzsch reaction
spellingShingle Devalina Ray
Ram Naresh Yadav
Bimal Krishna Banik
Vitamin C-Catalyzed Hantzsch reaction under microwave condition: A greener access to 1,4-Dihydropyridines
Results in Chemistry
1
4-Dihydropyridine (DHP)
Vitamin C
Microwave synthesis
Hantzsch reaction
title Vitamin C-Catalyzed Hantzsch reaction under microwave condition: A greener access to 1,4-Dihydropyridines
title_full Vitamin C-Catalyzed Hantzsch reaction under microwave condition: A greener access to 1,4-Dihydropyridines
title_fullStr Vitamin C-Catalyzed Hantzsch reaction under microwave condition: A greener access to 1,4-Dihydropyridines
title_full_unstemmed Vitamin C-Catalyzed Hantzsch reaction under microwave condition: A greener access to 1,4-Dihydropyridines
title_short Vitamin C-Catalyzed Hantzsch reaction under microwave condition: A greener access to 1,4-Dihydropyridines
title_sort vitamin c catalyzed hantzsch reaction under microwave condition a greener access to 1 4 dihydropyridines
topic 1
4-Dihydropyridine (DHP)
Vitamin C
Microwave synthesis
Hantzsch reaction
url http://www.sciencedirect.com/science/article/pii/S2211715622000492
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AT ramnareshyadav vitaminccatalyzedhantzschreactionundermicrowaveconditionagreeneraccessto14dihydropyridines
AT bimalkrishnabanik vitaminccatalyzedhantzschreactionundermicrowaveconditionagreeneraccessto14dihydropyridines