GFAP serves as a structural element of tunneling nanotubes between glioblastoma cells and could play a role in the intercellular transfer of mitochondria

GFAP serves as a structural element of tunneling nanotubes between glioblastoma cells and could play a role in the intercellular transfer of mitochondria

Tunneling nanotubes (TNTs) are long F-actin-positive plasma membrane bridges connecting distant cells, allowing the intercellular transfer of cellular cargoes, and are found to be involved in glioblastoma (GBM) intercellular crosstalk. Glial fibrillary acid protein (GFAP) is a key intermediate filam...

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Bibliographic Details
Main Authors: L. Simone, D. L. Capobianco, F. Di Palma, E. Binda, F. G. Legnani, A. L. Vescovi, M. Svelto, F. Pisani
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
cell-to-cell crosstalk
tunneling nanotubes
glioblastoma
GFAP
mitochondria
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1221671/full

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