Berberine promotes M2 macrophage polarisation through the IL-4-STAT6 signalling pathway in ulcerative colitis treatment

Berberine promotes M2 macrophage polarisation through the IL-4-STAT6 signalling pathway in ulcerative colitis treatment

Aim: This study focusses on the anti-inflammatory and immune-modulatory roles of berberine (BBR) in ulcerative colitis (UC) treatment. Additionally, the underlying mechanisms of BBR were systematically explored. Methods: A 3% (w/v) dextran sodium sulphate (DSS) solution was used for establishing the...

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Bibliographic Details
Main Authors: Kai Xiong, Jia Deng, Tinghui Yue, Wenting Hu, Xinglin Zeng, Tao Yang, Tianbao Xiao
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Heliyon
Subjects:
Ulcerative colitis
Berberine
Inflammation
Macrophages
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402301383X

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