A Case Report of Changes of Dysplasia and Multiple Malignancies in a Patient with Epidermodysplasia Verruciformis

Introduction: Epidermodysplasia verruciformis(EV) is a very rare, chronic and inherited disorder characterized by widespread and persistent HPV infection. EV Patients present with widespread, discrete or confluent lesions that clinically indistinguishable from plane warts , scaly hyper or hypopigmen...

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Main Authors: Akram Ansar, Mahmood Farshchian, Sasan Farahnaki
Format: Article
Language:fas
Published: Hamadan University of Medical Sciences 2008-06-01
Series:پزشکی بالینی ابن سینا
Subjects:
Online Access:http://sjh.umsha.ac.ir/article-1-388-en.html
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author Akram Ansar
Mahmood Farshchian
Sasan Farahnaki
author_facet Akram Ansar
Mahmood Farshchian
Sasan Farahnaki
author_sort Akram Ansar
collection DOAJ
description Introduction: Epidermodysplasia verruciformis(EV) is a very rare, chronic and inherited disorder characterized by widespread and persistent HPV infection. EV Patients present with widespread, discrete or confluent lesions that clinically indistinguishable from plane warts , scaly hyper or hypopigmented macules closely resemble pityriasis versicolor, and thicker plaques may resemble seborrbeic keratosis. Susceptibility to the virus is inherited, usually autosomal recessive. The disease usually manifests in childhood and continue throughout the life. The most important complication is cutaneous changes of dysplasia and malignancy. Case Report: We report a 19 years old boy with clinical and histopathological findings compatible with EV and cutaneous changes of dysplasia and malignancy. Conclusion: We concluded that in patients with combination of plane warts, pityriasis versicolor-like lesions and reddish plaques, it may be considered EV, and it is recommended to evaluate cutaneous changes of dysplasia and malignancy.
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spelling doaj.art-34705180abcd429bbdc60830c738870f2022-12-22T00:57:16ZfasHamadan University of Medical Sciencesپزشکی بالینی ابن سینا2588-722X2588-72382008-06-011516669A Case Report of Changes of Dysplasia and Multiple Malignancies in a Patient with Epidermodysplasia VerruciformisAkram Ansar0Mahmood Farshchian1Sasan Farahnaki2 Introduction: Epidermodysplasia verruciformis(EV) is a very rare, chronic and inherited disorder characterized by widespread and persistent HPV infection. EV Patients present with widespread, discrete or confluent lesions that clinically indistinguishable from plane warts , scaly hyper or hypopigmented macules closely resemble pityriasis versicolor, and thicker plaques may resemble seborrbeic keratosis. Susceptibility to the virus is inherited, usually autosomal recessive. The disease usually manifests in childhood and continue throughout the life. The most important complication is cutaneous changes of dysplasia and malignancy. Case Report: We report a 19 years old boy with clinical and histopathological findings compatible with EV and cutaneous changes of dysplasia and malignancy. Conclusion: We concluded that in patients with combination of plane warts, pityriasis versicolor-like lesions and reddish plaques, it may be considered EV, and it is recommended to evaluate cutaneous changes of dysplasia and malignancy.http://sjh.umsha.ac.ir/article-1-388-en.htmlhuman epidermodysplasia verruciformispapilloma virustinea versicolor
spellingShingle Akram Ansar
Mahmood Farshchian
Sasan Farahnaki
A Case Report of Changes of Dysplasia and Multiple Malignancies in a Patient with Epidermodysplasia Verruciformis
پزشکی بالینی ابن سینا
human epidermodysplasia verruciformis
papilloma virus
tinea versicolor
title A Case Report of Changes of Dysplasia and Multiple Malignancies in a Patient with Epidermodysplasia Verruciformis
title_full A Case Report of Changes of Dysplasia and Multiple Malignancies in a Patient with Epidermodysplasia Verruciformis
title_fullStr A Case Report of Changes of Dysplasia and Multiple Malignancies in a Patient with Epidermodysplasia Verruciformis
title_full_unstemmed A Case Report of Changes of Dysplasia and Multiple Malignancies in a Patient with Epidermodysplasia Verruciformis
title_short A Case Report of Changes of Dysplasia and Multiple Malignancies in a Patient with Epidermodysplasia Verruciformis
title_sort case report of changes of dysplasia and multiple malignancies in a patient with epidermodysplasia verruciformis
topic human epidermodysplasia verruciformis
papilloma virus
tinea versicolor
url http://sjh.umsha.ac.ir/article-1-388-en.html
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