The Effect of Energy Drink on Histomorphological Changes in Skeletal Muscles of Wistar Albino Rats
Objective: To observe the histomorphological alterations induced by consumption of energy drinks on skeletal muscles of Albino rats. Study Design:An experimental study. Place and Duration of Study: The study was conducted by the Department of Anatomy in collaboration with the animal house of Liaqu...
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| Format: | Article |
| Language: | English |
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Riphah International University, Islamabad
2024-01-01
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| Series: | Journal of Islamic International Medical College |
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| Online Access: | https://journals.riphah.edu.pk/index.php/jiimc/article/view/1779 |
| _version_ | 1797367594053795840 |
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| author | Fatima Rehman , Zia Ul Islam , Lubna Faisal , Ayesha Mehwish , Sadia Rehman , Maryam Faiz Qureshi |
| author_facet | Fatima Rehman , Zia Ul Islam , Lubna Faisal , Ayesha Mehwish , Sadia Rehman , Maryam Faiz Qureshi |
| author_sort | Fatima Rehman , Zia Ul Islam , Lubna Faisal , Ayesha Mehwish , Sadia Rehman , Maryam Faiz Qureshi |
| collection | DOAJ |
| description | Objective: To observe the histomorphological alterations induced by consumption of energy drinks on skeletal muscles of Albino rats.
Study Design:An experimental study.
Place and Duration of Study: The study was conducted by the Department of Anatomy in collaboration with the animal house of Liaquat national hospital and medical college (LNH&MC), Karachi from November 2 to December 1 2020.
Materials and Methods: For the study, 30 adult male Wistar Albino rats weighing between 140 and 200 grammes were allocated evenly into 3 groups. Group A served as control, kept on a regular laboratory diet. Group B served as a low dose treated group receiving energy drink at a dose of 7.5ml/day while group C received a high dose of drink i-e 15ml/day via gastric tube. All the animals were sacrificed following completion of the experimental period and were subjected to microscopic examination for histo-morphological study. Data was analyzed by using SPSS version 25.
Results: The Hematoxylin and Eosin (H&E) stained sections revealed significant structural and parenchymal damage in skeletal muscle tissue. The regular parallel arrangement of skeletal muscle fibers was lost with the disappearance of nuclei. Dilated and congested blood vessels were observed in the treated tissues. Infiltration of mononuclear cells was also observed suggesting the inflammatory changes in the tissues of animals treated with caffeinated beverages in the present study.
Conclusion: The consumption of energy drinks produces a significant histo-morphological alteration in the skeletal muscles of Wistar Albino rats |
| first_indexed | 2024-03-08T17:20:35Z |
| format | Article |
| id | doaj.art-34741a8f1b4248e0a02a08a88ec23a29 |
| institution | Directory Open Access Journal |
| issn | 1815-4018 2410-5422 |
| language | English |
| last_indexed | 2024-03-08T17:20:35Z |
| publishDate | 2024-01-01 |
| publisher | Riphah International University, Islamabad |
| record_format | Article |
| series | Journal of Islamic International Medical College |
| spelling | doaj.art-34741a8f1b4248e0a02a08a88ec23a292024-01-03T06:18:38ZengRiphah International University, IslamabadJournal of Islamic International Medical College1815-40182410-54222024-01-01184246251https://doi.org/10.57234/jiimc.december23.1779The Effect of Energy Drink on Histomorphological Changes in Skeletal Muscles of Wistar Albino RatsFatima Rehman , Zia Ul Islam , Lubna Faisal , Ayesha Mehwish , Sadia Rehman , Maryam Faiz Qureshi0Liaquat National Hospital and Medical College, KarachiObjective: To observe the histomorphological alterations induced by consumption of energy drinks on skeletal muscles of Albino rats. Study Design:An experimental study. Place and Duration of Study: The study was conducted by the Department of Anatomy in collaboration with the animal house of Liaquat national hospital and medical college (LNH&MC), Karachi from November 2 to December 1 2020. Materials and Methods: For the study, 30 adult male Wistar Albino rats weighing between 140 and 200 grammes were allocated evenly into 3 groups. Group A served as control, kept on a regular laboratory diet. Group B served as a low dose treated group receiving energy drink at a dose of 7.5ml/day while group C received a high dose of drink i-e 15ml/day via gastric tube. All the animals were sacrificed following completion of the experimental period and were subjected to microscopic examination for histo-morphological study. Data was analyzed by using SPSS version 25. Results: The Hematoxylin and Eosin (H&E) stained sections revealed significant structural and parenchymal damage in skeletal muscle tissue. The regular parallel arrangement of skeletal muscle fibers was lost with the disappearance of nuclei. Dilated and congested blood vessels were observed in the treated tissues. Infiltration of mononuclear cells was also observed suggesting the inflammatory changes in the tissues of animals treated with caffeinated beverages in the present study. Conclusion: The consumption of energy drinks produces a significant histo-morphological alteration in the skeletal muscles of Wistar Albino ratshttps://journals.riphah.edu.pk/index.php/jiimc/article/view/1779congested blood vesselsenergy drinkloss of nucleimononuclear cellsskeletal muscles. |
| spellingShingle | Fatima Rehman , Zia Ul Islam , Lubna Faisal , Ayesha Mehwish , Sadia Rehman , Maryam Faiz Qureshi The Effect of Energy Drink on Histomorphological Changes in Skeletal Muscles of Wistar Albino Rats Journal of Islamic International Medical College congested blood vessels energy drink loss of nuclei mononuclear cells skeletal muscles. |
| title | The Effect of Energy Drink on Histomorphological Changes in Skeletal Muscles of Wistar Albino Rats |
| title_full | The Effect of Energy Drink on Histomorphological Changes in Skeletal Muscles of Wistar Albino Rats |
| title_fullStr | The Effect of Energy Drink on Histomorphological Changes in Skeletal Muscles of Wistar Albino Rats |
| title_full_unstemmed | The Effect of Energy Drink on Histomorphological Changes in Skeletal Muscles of Wistar Albino Rats |
| title_short | The Effect of Energy Drink on Histomorphological Changes in Skeletal Muscles of Wistar Albino Rats |
| title_sort | effect of energy drink on histomorphological changes in skeletal muscles of wistar albino rats |
| topic | congested blood vessels energy drink loss of nuclei mononuclear cells skeletal muscles. |
| url | https://journals.riphah.edu.pk/index.php/jiimc/article/view/1779 |
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