A Levee to the Flood: Pre-injury Neuroinflammation and Immune Stress Influence Traumatic Brain Injury Outcome

A Levee to the Flood: Pre-injury Neuroinflammation and Immune Stress Influence Traumatic Brain Injury Outcome

Increasing evidence demonstrates that aging influences the brain's response to traumatic brain injury (TBI), setting the stage for neurodegenerative pathology like Alzheimer's disease (AD). This topic is often dominated by discussions of post-injury aging and inflammation, which can dimini...

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Bibliographic Details
Main Authors: Samuel Houle, Olga N. Kokiko-Cochran
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Aging Neuroscience
Subjects:
traumatic brain injury
inflammation
microglia
mitochondria
Alzheimer's disease
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.788055/full

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