Squalene in oil-based adjuvant improves the immunogenicity of SARS-CoV-2 RBD and confirms safety in animal models

Squalene in oil-based adjuvant improves the immunogenicity of SARS-CoV-2 RBD and confirms safety in animal models

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COVID-19 pandemic has accelerated the development of vaccines against its etiologic agent, SARS-CoV-2. However, the emergence of new variants of the virus lead to the generation of new alternatives to improve the current sub-unit vaccines in development. In the present report, the immunogenicity of...

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Main Authors: Ricardo Choque-Guevara, Astrid Poma-Acevedo, Ricardo Montesinos-Millán, Dora Rios-Matos, Kristel Gutiérrez-Manchay, Angela Montalvan-Avalos, Stefany Quiñones-Garcia, Maria de Grecia Cauti-Mendoza, Andres Agurto-Arteaga, Ingrid Ramirez-Ortiz, Manuel Criollo-Orozco, Edison Huaccachi-Gonzales, Yomara K. Romero, Norma Perez-Martinez, Gisela Isasi-Rivas, Yacory Sernaque-Aguilar, Doris Villanueva-Pérez, Freddy Ygnacio, Katherine Vallejos-Sánchez, Manolo Fernández-Sánchez, Luis A. Guevara-Sarmiento, Manolo Fernández-Díaz, Mirko Zimic, for the COVID-19 Working Group in Perú
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397949/?tool=EBI

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