High Resolution Computed Tomography Lung Spectrum in Symptomatic Adult HIV-Positive Patients in South-East Asian Nation
Background: Pulmonary infections remain a leading cause of morbidity and mortality and one of the most frequent causes of hospital admission in HIV infected people worldwide. HRCT may be useful in the evaluation of patients with suspected pulmonary disease. The aim of given study was to determi...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2014-06-01
|
| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/4518/9397_CE(Ra)_F(H)_PF1(AGH)_PFA(AK).pdf |
| _version_ | 1828498146509979648 |
|---|---|
| author | Swapndeep Singh Atwal Swapnil Puranik Ramavathu Kumar Venu Madhav Abhinetri KSV B. B. Sharma Umesh Chand Garga |
| author_facet | Swapndeep Singh Atwal Swapnil Puranik Ramavathu Kumar Venu Madhav Abhinetri KSV B. B. Sharma Umesh Chand Garga |
| author_sort | Swapndeep Singh Atwal |
| collection | DOAJ |
| description | Background: Pulmonary infections remain a leading cause of
morbidity and mortality and one of the most frequent causes of
hospital admission in HIV infected people worldwide. HRCT may
be useful in the evaluation of patients with suspected pulmonary
disease.
The aim of given study was to determine the High Resolution
Computed Tomography spectrum of lung parenchymal and
interstitial imaging findings in HIV infected patients presented
with chest symptoms.
Materials and Methods: This study was conducted in a tertiary
health care centre, New Delhi, India. The study consisted of
45 patients. A thorough clinical history of all the HIV positive
patients presenting with suspicion of pulmonary disease was
taken. General physical and respiratory system examination of
all patients was done
HRCT scans of the chest were done in all the cases taken in the
study.
Results: Maximum number of patients was in age group 31-40
years (24 cases). Out of 45 patients included in our study, 32
(71%) were male and 13 (29%) were female.
In our series of 45 patients, 62.2% of patients were diagnosed as
having pulmonary tuberculosis, followed by bacterial infection in
20% cases and Pneumocystis jiroveci pneumonia (PJP) in 8.9%
patients, while 8.9% of the study did not reveal any significant
abnormality.
Maximum number (22/28) of patients with pulmonary tuberculosis
were indentified to have nodular opacities.
The most common HRCT finding in bacterial infection was lobar
consolidation.
The most common HRCT finding in patients with PCP was diffuse
ground glass opacities in mosaic pattern of distribution.
Conclusion: HRCT is a highly sensitive tool for detecting
lung parenchymal and interstitial lesions and allows better
characterization of the lesions.
HRCT findings should always be correlated with clinical findings,
CD4 counts and other available investigations before arriving at a
diagnosis or differential diagnosis. |
| first_indexed | 2024-12-11T13:01:37Z |
| format | Article |
| id | doaj.art-347815e96a23494abbcc52bec9aa5011 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-11T13:01:37Z |
| publishDate | 2014-06-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-347815e96a23494abbcc52bec9aa50112022-12-22T01:06:27ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2014-06-0186RC12RC1610.7860/JCDR/2014/9397.4518High Resolution Computed Tomography Lung Spectrum in Symptomatic Adult HIV-Positive Patients in South-East Asian NationSwapndeep Singh Atwal0Swapnil Puranik1Ramavathu Kumar Venu Madhav2Abhinetri KSV3B. B. Sharma4Umesh Chand Garga5Senior Resident, Department of Radiology, PGIMER and Dr. Ram Manohar Lohia Hospital, New Delhi, India.Post Graduate, Department of Radiology, Government Medical College, Kota (Rajasthan), India.Senior Resident, Department of Radiology, PGIMER and Dr. Ram Manohar Lohia Hospital, New Delhi, India.Post Graduate, Department of Radiology, PGIMER and Dr. Ram Manohar Lohia Hospital, New Delhi, India.Associate Professor, Department of Radiology, PGIMER and Dr. Ram Manohar Lohia Hospital, New Delhi, India.Professor and Head of Department, Department of Radiology, PGIMER and Dr. Ram Manohar Lohia Hospital, New Delhi, India.Background: Pulmonary infections remain a leading cause of morbidity and mortality and one of the most frequent causes of hospital admission in HIV infected people worldwide. HRCT may be useful in the evaluation of patients with suspected pulmonary disease. The aim of given study was to determine the High Resolution Computed Tomography spectrum of lung parenchymal and interstitial imaging findings in HIV infected patients presented with chest symptoms. Materials and Methods: This study was conducted in a tertiary health care centre, New Delhi, India. The study consisted of 45 patients. A thorough clinical history of all the HIV positive patients presenting with suspicion of pulmonary disease was taken. General physical and respiratory system examination of all patients was done HRCT scans of the chest were done in all the cases taken in the study. Results: Maximum number of patients was in age group 31-40 years (24 cases). Out of 45 patients included in our study, 32 (71%) were male and 13 (29%) were female. In our series of 45 patients, 62.2% of patients were diagnosed as having pulmonary tuberculosis, followed by bacterial infection in 20% cases and Pneumocystis jiroveci pneumonia (PJP) in 8.9% patients, while 8.9% of the study did not reveal any significant abnormality. Maximum number (22/28) of patients with pulmonary tuberculosis were indentified to have nodular opacities. The most common HRCT finding in bacterial infection was lobar consolidation. The most common HRCT finding in patients with PCP was diffuse ground glass opacities in mosaic pattern of distribution. Conclusion: HRCT is a highly sensitive tool for detecting lung parenchymal and interstitial lesions and allows better characterization of the lesions. HRCT findings should always be correlated with clinical findings, CD4 counts and other available investigations before arriving at a diagnosis or differential diagnosis.https://jcdr.net/articles/PDF/4518/9397_CE(Ra)_F(H)_PF1(AGH)_PFA(AK).pdfbacterial infectionhigh resolution computed tomographyhuman immunodeficiency viruspneumocystis jiroveci pneumoniapulmonary tuberculosisradiologic patterns |
| spellingShingle | Swapndeep Singh Atwal Swapnil Puranik Ramavathu Kumar Venu Madhav Abhinetri KSV B. B. Sharma Umesh Chand Garga High Resolution Computed Tomography Lung Spectrum in Symptomatic Adult HIV-Positive Patients in South-East Asian Nation Journal of Clinical and Diagnostic Research bacterial infection high resolution computed tomography human immunodeficiency virus pneumocystis jiroveci pneumonia pulmonary tuberculosis radiologic patterns |
| title | High Resolution Computed Tomography Lung Spectrum in Symptomatic Adult HIV-Positive Patients in South-East Asian Nation |
| title_full | High Resolution Computed Tomography Lung Spectrum in Symptomatic Adult HIV-Positive Patients in South-East Asian Nation |
| title_fullStr | High Resolution Computed Tomography Lung Spectrum in Symptomatic Adult HIV-Positive Patients in South-East Asian Nation |
| title_full_unstemmed | High Resolution Computed Tomography Lung Spectrum in Symptomatic Adult HIV-Positive Patients in South-East Asian Nation |
| title_short | High Resolution Computed Tomography Lung Spectrum in Symptomatic Adult HIV-Positive Patients in South-East Asian Nation |
| title_sort | high resolution computed tomography lung spectrum in symptomatic adult hiv positive patients in south east asian nation |
| topic | bacterial infection high resolution computed tomography human immunodeficiency virus pneumocystis jiroveci pneumonia pulmonary tuberculosis radiologic patterns |
| url | https://jcdr.net/articles/PDF/4518/9397_CE(Ra)_F(H)_PF1(AGH)_PFA(AK).pdf |
| work_keys_str_mv | AT swapndeepsinghatwal highresolutioncomputedtomographylungspectruminsymptomaticadulthivpositivepatientsinsoutheastasiannation AT swapnilpuranik highresolutioncomputedtomographylungspectruminsymptomaticadulthivpositivepatientsinsoutheastasiannation AT ramavathukumarvenumadhav highresolutioncomputedtomographylungspectruminsymptomaticadulthivpositivepatientsinsoutheastasiannation AT abhinetriksv highresolutioncomputedtomographylungspectruminsymptomaticadulthivpositivepatientsinsoutheastasiannation AT bbsharma highresolutioncomputedtomographylungspectruminsymptomaticadulthivpositivepatientsinsoutheastasiannation AT umeshchandgarga highresolutioncomputedtomographylungspectruminsymptomaticadulthivpositivepatientsinsoutheastasiannation |