Outcomes of incoming and outgoing second opinions from a UK liver transplant centre

Objective Second transplant centre opinions (STCOs) for patients declined for liver transplantation are infrequent. We aimed to identify STCOs outcomes from a tertiary transplant centre.Design Referrals between 2012 and 2020 to Birmingham Unit were reviewed. Incoming: all referrals from out-of-regio...

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Main Authors: Alexander Boyd, Neil Rajoriya, James Neuberger, Matthew J Armstrong, Kerry Webb, Sara Mahgoub, Sean Morris, Alessandro Parente
Format: Article
Language:English
Published: BMJ Publishing Group 2022-04-01
Series:BMJ Open Gastroenterology
Online Access:https://bmjopengastro.bmj.com/content/9/1/e000987.full
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author Alexander Boyd
Neil Rajoriya
James Neuberger
Matthew J Armstrong
Kerry Webb
Sara Mahgoub
Sean Morris
Alessandro Parente
author_facet Alexander Boyd
Neil Rajoriya
James Neuberger
Matthew J Armstrong
Kerry Webb
Sara Mahgoub
Sean Morris
Alessandro Parente
author_sort Alexander Boyd
collection DOAJ
description Objective Second transplant centre opinions (STCOs) for patients declined for liver transplantation are infrequent. We aimed to identify STCOs outcomes from a tertiary transplant centre.Design Referrals between 2012 and 2020 to Birmingham Unit were reviewed. Incoming: all referrals from out-of-region centres were collated. Outgoing: patients not listed in Birmingham were reviewed to identify referrals for STCOs to the other UK centres (A–F).Results 2535 patients were assessed for liver transplantation during the study period. Incoming: among 1751 referrals, 23 STCOs (17 unit A, 3 unit B, 1 unit C, 1 unit D and 1 unit E) were provided by Birmingham. Of the STCOs, 13/23 (57%) patients remained unsuitable for transplantation. Therefore, 10/23 (43%) underwent a second liver transplant assessment, of whom five (50%) were still deemed unsuitable, three (30%) listed (one transplanted) and two (20%) died preassessment. Outgoing: among 426 patients not listed, eight (1.8%) patients were referred for STCO (4 unit E, 2 unit B, 1 unit D, 1 unit A). Three (38%) were listed, two (25%) were assessed and declined, two (25%) were unsuitable for assessment and one (12.5%) died while waiting. Combining incoming and outgoing Birmingham STCOs (n=31), six (19%) of STCOs were listed in a second centre.Conclusion Second transplant centre opinions are rare with the majority still deemed unsuitable for liver transplantation. This highlights potential resource implications especially when undergoing a full second formal assessment. A streamlined STCO process with sharing of investigations and use of telemedicine in appropriate patients may allow for greater transparency, quicker decision making and less use of labour-intensive resources.
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spelling doaj.art-3478bc510fe34b4db545275dc44f37882022-12-22T04:31:59ZengBMJ Publishing GroupBMJ Open Gastroenterology2054-47742022-04-019110.1136/bmjgast-2022-000987Outcomes of incoming and outgoing second opinions from a UK liver transplant centreAlexander Boyd0Neil Rajoriya1James Neuberger2Matthew J Armstrong3Kerry Webb4Sara Mahgoub5Sean Morris6Alessandro Parente7Liver Unit, Queen Elizabeth Hospital Birmingham, Birmingham, UKLiver Unit, Queen Elizabeth Hospital Birmingham, Birmingham, UKLiver Unit, Queen Elizabeth Hospital Birmingham, Birmingham, UKLiver Unit, Queen Elizabeth Hospital Birmingham, Birmingham, UKLiver Unit, Queen Elizabeth Hospital Birmingham, Birmingham, UKLiver Unit, Queen Elizabeth Hospital Birmingham, Birmingham, UKLiver Unit, Queen Elizabeth Hospital Birmingham, Birmingham, UKLiver Unit, Queen Elizabeth Hospital Birmingham, Birmingham, UKObjective Second transplant centre opinions (STCOs) for patients declined for liver transplantation are infrequent. We aimed to identify STCOs outcomes from a tertiary transplant centre.Design Referrals between 2012 and 2020 to Birmingham Unit were reviewed. Incoming: all referrals from out-of-region centres were collated. Outgoing: patients not listed in Birmingham were reviewed to identify referrals for STCOs to the other UK centres (A–F).Results 2535 patients were assessed for liver transplantation during the study period. Incoming: among 1751 referrals, 23 STCOs (17 unit A, 3 unit B, 1 unit C, 1 unit D and 1 unit E) were provided by Birmingham. Of the STCOs, 13/23 (57%) patients remained unsuitable for transplantation. Therefore, 10/23 (43%) underwent a second liver transplant assessment, of whom five (50%) were still deemed unsuitable, three (30%) listed (one transplanted) and two (20%) died preassessment. Outgoing: among 426 patients not listed, eight (1.8%) patients were referred for STCO (4 unit E, 2 unit B, 1 unit D, 1 unit A). Three (38%) were listed, two (25%) were assessed and declined, two (25%) were unsuitable for assessment and one (12.5%) died while waiting. Combining incoming and outgoing Birmingham STCOs (n=31), six (19%) of STCOs were listed in a second centre.Conclusion Second transplant centre opinions are rare with the majority still deemed unsuitable for liver transplantation. This highlights potential resource implications especially when undergoing a full second formal assessment. A streamlined STCO process with sharing of investigations and use of telemedicine in appropriate patients may allow for greater transparency, quicker decision making and less use of labour-intensive resources.https://bmjopengastro.bmj.com/content/9/1/e000987.full
spellingShingle Alexander Boyd
Neil Rajoriya
James Neuberger
Matthew J Armstrong
Kerry Webb
Sara Mahgoub
Sean Morris
Alessandro Parente
Outcomes of incoming and outgoing second opinions from a UK liver transplant centre
BMJ Open Gastroenterology
title Outcomes of incoming and outgoing second opinions from a UK liver transplant centre
title_full Outcomes of incoming and outgoing second opinions from a UK liver transplant centre
title_fullStr Outcomes of incoming and outgoing second opinions from a UK liver transplant centre
title_full_unstemmed Outcomes of incoming and outgoing second opinions from a UK liver transplant centre
title_short Outcomes of incoming and outgoing second opinions from a UK liver transplant centre
title_sort outcomes of incoming and outgoing second opinions from a uk liver transplant centre
url https://bmjopengastro.bmj.com/content/9/1/e000987.full
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