Genetic factors affecting storage and utilization of lipids during dormancy in Mycobacterium tuberculosis

Genetic factors affecting storage and utilization of lipids during dormancy in Mycobacterium tuberculosis

ABSTRACT Mycobacterium tuberculosis (Mtb) can adopt a non-growing dormant state during infection that may be critical to both active and latent tuberculosis. During dormancy, Mtb is widely tolerant toward antibiotics, a significant obstacle in current anti-tubercular drug regimens, and retains the a...

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Main Authors: Alexander Sturm, Penny Sun, Julian Avila-Pacheco, Anne E. Clatworthy, Zohar Bloom-Ackermann, Michael G. Wuo, James E. Gomez, Soomin Jin, Clary B. Clish, Laura L. Kiessling, Deborah T. Hung
Format: Article
Language:English
Published: American Society for Microbiology 2024-02-01
Series:mBio
Subjects:
Mycobacterium tuberculosis
dormancy
lipid metabolism
Online Access:https://journals.asm.org/doi/10.1128/mbio.03208-23

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