Efficacy of Compound Honey Syrup on Pulmonary Symptoms and Body Mass Index in Cystic Fibrosis Patients: A Clinical Trial
Background: Patients with Cystic Fibrosis (CF) often have respiratory tract infections and bacterial colonization requiring antibiotic treatment. The use of complementary treatments such as Compound Honey Syrup (CHS) in Persian medicine is increasing in the treatment of diseases. This study aimed to...
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2023-08-01
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| Series: | International Journal of Pediatrics |
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| Online Access: | https://ijp.mums.ac.ir/article_22872_b1e79d950de9a5a368b73ea51bf9819c.pdf |
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| author | Saeed Sadr Shahpar Kaveh Nafise Fadavi Hanieh Tahermohammadi Seyed Ahmad Tabatabaei Ghamartaj Khanbabaei Alireza Eshghi Matin pourghasem Parisa Honarpisheh Mohammad Nikpendar |
| author_facet | Saeed Sadr Shahpar Kaveh Nafise Fadavi Hanieh Tahermohammadi Seyed Ahmad Tabatabaei Ghamartaj Khanbabaei Alireza Eshghi Matin pourghasem Parisa Honarpisheh Mohammad Nikpendar |
| author_sort | Saeed Sadr |
| collection | DOAJ |
| description | Background: Patients with Cystic Fibrosis (CF) often have respiratory tract infections and bacterial colonization requiring antibiotic treatment. The use of complementary treatments such as Compound Honey Syrup (CHS) in Persian medicine is increasing in the treatment of diseases. This study aimed to assess the effects of Compound Honey Syrup (CHS) on CF-induced changes in pulmonary symptoms, and Body Mass Index (BMI) in children.Method: In a before/after clinical trial, 44 children aged ≥6 suffering from CF were included. They were referred to Mofid children's Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran, between March 2020 and March 2021. The patients received their standard treatment, plus CHS (prescribed at 5-10 cc dose twice daily according to the weight of children (weight over 30 kg 10 ccs and under 30 kg 5 ccs) for 12 weeks. The Cystic Fibrosis Questionnaire-Revised (CFQ-R) was used to determine the Severity of pulmonary symptoms. Moreover, BMIs were compared before and after CHS intervention.Results: CHS administration for 12 weeks improved daily cough (P=0.000), sputum production (P=0.003), wheezing (P=0.000), difficulty breathing (P=0.002), and night-time cough scores (P=0.004) considerably in CF patients after intervention. Moreover, CHS consumption increased BMI (P=0.000) in these patients.Conclusion: It can be concluded that compound honey syrup can be a safe and effective complementary medicine to improve pulmonary symptoms and nutritional status of cystic fibrosis patients. In order to confirm these results, it is recommended to conduct more studies with larger sample sizes in order to evaluate the effect of CHS on pulmonary symptoms and BMI in cystic fibrosis patients. |
| first_indexed | 2024-03-12T05:33:15Z |
| format | Article |
| id | doaj.art-347d02c2fba045ff9ec615e95db0b0bd |
| institution | Directory Open Access Journal |
| issn | 2345-5047 2345-5055 |
| language | English |
| last_indexed | 2024-03-12T05:33:15Z |
| publishDate | 2023-08-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | International Journal of Pediatrics |
| spelling | doaj.art-347d02c2fba045ff9ec615e95db0b0bd2023-09-03T06:34:09ZengMashhad University of Medical SciencesInternational Journal of Pediatrics2345-50472345-50552023-08-01118181801818810.22038/ijp.2023.72361.526922872Efficacy of Compound Honey Syrup on Pulmonary Symptoms and Body Mass Index in Cystic Fibrosis Patients: A Clinical TrialSaeed Sadr0Shahpar Kaveh1Nafise Fadavi2Hanieh Tahermohammadi3Seyed Ahmad Tabatabaei4Ghamartaj Khanbabaei5Alireza Eshghi6Matin pourghasem7Parisa Honarpisheh8Mohammad Nikpendar9Department of Pediatric Pulmonology, Mofid Children’s Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IranDepartment of Traditional Medicine, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, IranRajaei Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IranChronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, IranDepartment of Pediatric Pulmonology, Mofid Children’s Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Department of Pediatric Pulmonology, Mofid Children’s Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Department of Pediatric Pulmonology, Mofid Children’s Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IranDepartment of Pediatric Pulmonology, Mofid Children’s Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Department of Pediatric Pulmonology, Mofid Children’s Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IranDepartment of Pediatric Pulmonology, Mofid Children’s Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IranBackground: Patients with Cystic Fibrosis (CF) often have respiratory tract infections and bacterial colonization requiring antibiotic treatment. The use of complementary treatments such as Compound Honey Syrup (CHS) in Persian medicine is increasing in the treatment of diseases. This study aimed to assess the effects of Compound Honey Syrup (CHS) on CF-induced changes in pulmonary symptoms, and Body Mass Index (BMI) in children.Method: In a before/after clinical trial, 44 children aged ≥6 suffering from CF were included. They were referred to Mofid children's Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran, between March 2020 and March 2021. The patients received their standard treatment, plus CHS (prescribed at 5-10 cc dose twice daily according to the weight of children (weight over 30 kg 10 ccs and under 30 kg 5 ccs) for 12 weeks. The Cystic Fibrosis Questionnaire-Revised (CFQ-R) was used to determine the Severity of pulmonary symptoms. Moreover, BMIs were compared before and after CHS intervention.Results: CHS administration for 12 weeks improved daily cough (P=0.000), sputum production (P=0.003), wheezing (P=0.000), difficulty breathing (P=0.002), and night-time cough scores (P=0.004) considerably in CF patients after intervention. Moreover, CHS consumption increased BMI (P=0.000) in these patients.Conclusion: It can be concluded that compound honey syrup can be a safe and effective complementary medicine to improve pulmonary symptoms and nutritional status of cystic fibrosis patients. In order to confirm these results, it is recommended to conduct more studies with larger sample sizes in order to evaluate the effect of CHS on pulmonary symptoms and BMI in cystic fibrosis patients.https://ijp.mums.ac.ir/article_22872_b1e79d950de9a5a368b73ea51bf9819c.pdfcystic fibrosis,,,،compound honey syrup (chs),,,،respiratory symptoms,,,،body mass index (bmi) |
| spellingShingle | Saeed Sadr Shahpar Kaveh Nafise Fadavi Hanieh Tahermohammadi Seyed Ahmad Tabatabaei Ghamartaj Khanbabaei Alireza Eshghi Matin pourghasem Parisa Honarpisheh Mohammad Nikpendar Efficacy of Compound Honey Syrup on Pulmonary Symptoms and Body Mass Index in Cystic Fibrosis Patients: A Clinical Trial International Journal of Pediatrics cystic fibrosis,, ,،compound honey syrup (chs),, ,،respiratory symptoms,, ,،body mass index (bmi) |
| title | Efficacy of Compound Honey Syrup on Pulmonary Symptoms and Body Mass Index in Cystic Fibrosis Patients: A Clinical Trial |
| title_full | Efficacy of Compound Honey Syrup on Pulmonary Symptoms and Body Mass Index in Cystic Fibrosis Patients: A Clinical Trial |
| title_fullStr | Efficacy of Compound Honey Syrup on Pulmonary Symptoms and Body Mass Index in Cystic Fibrosis Patients: A Clinical Trial |
| title_full_unstemmed | Efficacy of Compound Honey Syrup on Pulmonary Symptoms and Body Mass Index in Cystic Fibrosis Patients: A Clinical Trial |
| title_short | Efficacy of Compound Honey Syrup on Pulmonary Symptoms and Body Mass Index in Cystic Fibrosis Patients: A Clinical Trial |
| title_sort | efficacy of compound honey syrup on pulmonary symptoms and body mass index in cystic fibrosis patients a clinical trial |
| topic | cystic fibrosis,, ,،compound honey syrup (chs),, ,،respiratory symptoms,, ,،body mass index (bmi) |
| url | https://ijp.mums.ac.ir/article_22872_b1e79d950de9a5a368b73ea51bf9819c.pdf |
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