Synthesis, Characterization and Biological Evaluation of Novel Benzamidine Derivatives: Newer Antibiotics for Periodontitis Treatment

Synthesis, Characterization and Biological Evaluation of Novel Benzamidine Derivatives: Newer Antibiotics for Periodontitis Treatment

Periodontal disease (PD) is complex polymicrobial disease which destroys tooth-supporting tissue. Although various synthetic inhibitors of periodontitis-triggering pathogens have been recognized, their undesirable side effects limit their application. Hence, the present study intended to perform the...

Full description

Bibliographic Details
Main Authors:	Mohammad Auwal Sa’ad, Ramasamy Kavitha, Shivkanya Fuloria, Neeraj Kumar Fuloria, Manickam Ravichandran, Pattabhiraman Lalitha
Format:	Article
Language:	English
Published:	MDPI AG 2022-02-01
Series:	Antibiotics
Subjects:	periodontitis benzamidine anti-bacterial agents cytotoxicity hydrazide aldehydes
Online Access:	https://www.mdpi.com/2079-6382/11/2/207

Similar Items

Synthesis, Characterization, Cytotoxicity Analysis and Evaluation of Novel Heterocyclic Derivatives of Benzamidine against Periodontal Disease Triggering Bacteria
by: Ramasamy Kavitha, et al.
Published: (2023-02-01)

Development of a Simple Protocol for Zymogram-Based Isolation and Characterization of Gingipains from <i>Porphyromonas gingivalis</i>: The Causative Agent of Periodontitis
by: Eng Sze Wei, et al.
Published: (2023-03-01)

SYNTHESIS AND ANTIMICROBIAL ACTIVITY EVALUATION OF SOME SCHIFF BASES DERIVED FROM 2-AMINOTHIAZOLE DERIVATIVES
by: Rajul Gupta, et al.
Published: (2013-07-01)

SYNTHESIS AND ANTIMICROBIAL ACTIVITY EVALUATION OF SOME SCHIFF BASES DERIVED FROM 2-AMINOTHIAZOLE DERIVATIVES
by: Rajul Gupta, et al.
Published: (2013-01-01)

Synthesis, characterization, cytotoxicity, and antiviral activity of new coumarin analogues against coronavirus
by: Mohammad Auwal Sa’ad, et al.
Published: (2024-08-01)

In vitro Immunobiological Studies of Novel 5-(5-nitrofuran-2-yl)-1, 3, 4- Thiadiazoles with Piperazinyl-Linked Benzamidine Substituents against Leishmania Major
by: Farzaneh Rezazadeh Marznaki, et al.
Published: (2013-12-01)

4-Methoxy-N,N′-diphenylbenzamidinium nitrate
by: Renata S. Silva, et al.
Published: (2016-09-01)

An investigation of the potential of rhodamine B hydrazide as a fluorescent probe for enhancing latent fingerprints
by: Nadeem Muhammad, et al.
Published: (2025-01-01)

Reactions of Tetracyanoethylene with Aliphatic and Aromatic Amines and Hydrazines and Chemical Transformations of Tetracyanoethylene Derivatives
by: Elizaveta Ivanova, et al.
Published: (2024-10-01)

5-Methyl-3,8-di-(2-amino-4-bromophenyl)-4,9-dioxa-1,2,6,7-tetraaza-5λ5-phosphaspiro[4.4]nona-2,7-diene
by: Sławomir Kasperowicz, et al.
Published: (2018-01-01)

Epidemiological Factors of Periodontal Disease Among South Indian Adults
by: Selvaraj S, et al.
Published: (2022-07-01)

Different Schiff Bases—Structure, Importance and Classification
by: Edyta Raczuk, et al.
Published: (2022-01-01)

Biological activities of meroterpenoids isolated from different sources
by: Neeraj Kumar Fuloria, et al.
Published: (2022-09-01)

Synthesis of oleanolic acid hydrazide-hydrazone hybrid derivatives and investigation of their cytotoxic effects on A549 human lung cancer cells
by: Şenol Halil, et al.
Published: (2022-01-01)

Synthesis of 6-chloro-2-oxo-1,2-dihydroquinoline-4-carbohydrazide
by: R. Bouhfid, et al.
Published: (2006-09-01)

Synthesis and in vitro antimycobacterial potential of novel hydrazones of eugenol
by: Sachin H. Rohane, et al.
Published: (2020-02-01)

ADJUNCTIVE USE OF ANTIBIOTICS IN PERIODONTAL THERAPY
by: Ece Barça, et al.
Published: (2015-10-01)

Novel Adamantane Derivatives: Synthesis, Cytotoxicity and Antimicrobial Properties
by: Łukasz Popiołek, et al.
Published: (2024-04-01)

Resveratrol-based Schiff base derivatives: Synthesis, characterization and cytotoxic study
by: Lamya A. Al-lehaib, et al.
Published: (2024-01-01)

Systemic antibiotic therapy in periodontics
by: Anoop Kapoor, et al.
Published: (2012-01-01)

A new class of dihaloquinolones bearing N'-aldehydoglycosylhydrazides, mercapto-1,2,4-triazole, oxadiazoline and a-amino ester precursors: synthesis and antimicrobial activity
by: Al-Soud Yaseen A., et al.
Published: (2003-01-01)

Synthesis , Characterization of Some Benzilyl Hydrazone Derived from Benzilic Acid Hydrazide
by: Salim Mohammed, et al.
Published: (2013-12-01)

Changes in Protonation States of In-Pathway Residues can Alter Ligand Binding Pathways Obtained From Spontaneous Binding Molecular Dynamics Simulations
by: Helena Girame, et al.
Published: (2022-07-01)

Assessment of Cytogenetic Damage to Exfoliated Gingival Cells in Patients with Chronic Generalized Periodontitis
by: Antonija Tadin, et al.
Published: (2021-01-01)

Heteroligand cobalt(II) complexes with some aromatic acid hydrazides and L-histidine
by: N.V. Troshanin, et al.
Published: (2019-03-01)

Synthesis and stereochemistry of benzamidines and acetamidines
by: Eva A. Oberlander, et al.
Published: (2000-08-01)

Synthesis and Characterization of Metal Particles Using Malic Acid-Derived Polyamides, Polyhydrazides, and Hydrazides
by: Muhammad Farhan Qadir, et al.
Published: (2024-12-01)

<i>N</i>′<sup>1</sup>,<i>N</i>′<sup>4</sup>-bis(2-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[<i>g</i>]pteridin-10(2<i>H</i>)-yl)ethylidene)succinohydrazide
by: Taishu Kawada, et al.
Published: (2022-08-01)

Síntese e caracterização de um novo complexo de platina (IV) a partir de seu análogo de platina (II) utilizando iodo molecular como agente oxidante: uma rota sintética interessante para obtenção de novos complexos de platina Synthesis and characterization of a novel platinum (IV) complex from its platinum (II) analogue using molecular iodine as an oxidizing agent: an interesting synthetic route for the preparation of new platinum complexes
by: Wendell Guerra, et al.
Published: (2007-02-01)

Synthesis and Characterization of Some New Hydrazides and Their Derivatives
by: Mohammad S. Al-Ajely, et al.
Published: (2017-03-01)

Nꞌ-{[2-(Piperidin-1-yl)quinolin-3-yl]methylene}pyridine-4-carbohydrazide
by: Rajiv K. Tonk, et al.
Published: (2012-01-01)

Polyamine-Derived Aminoaldehydes and Acrolein: Cytotoxicity, Reactivity and Analysis of the Induced Protein Modifications
by: Marek Šebela, et al.
Published: (2023-11-01)

Synthesis of a, a` Bis-(substituted benzylidene) cycloalkanones and derivatives /
by: Northaqifah Hasna Mohamed Khir, 1989-, et al.
Published: (2010)

Uso terapéutico de los antibióticos en el tratamiento periodontal. Revisión de la literatura Therapeutic use of antibiotics in periodontal treatment. Review of the literature
by: Lisbeth Sosa, et al.
Published: (2015-01-01)

Response to adjunctive antibiotic therapy along with nonsurgical periodontal therapy in the treatment of peri-implantitis and chronic periodontitis patients: An exploratory review
by: Geetanshu Sethi, et al.
Published: (2024-07-01)

Development of New Antimycobacterial Sulfonyl Hydrazones and 4-Methyl-1,2,3-thiadiazole-Based Hydrazone Derivatives
by: Violina T. Angelova, et al.
Published: (2022-04-01)

Natural Bioactive Thiazole-Based Peptides from Marine Resources: Structural and Pharmacological Aspects
by: Rajiv Dahiya, et al.
Published: (2020-06-01)

synthesis and characterization of 1,2,4-traiazole derivative from methyl benzaoate with sulfur bridge links
by: Ahmed Ahmed, et al.
Published: (2024-12-01)

Synthesis of some organic hydrazone compounds by using microwave radiation
by: Nihad Ismeal Taha
Published: (2015-06-01)

Green Chemistry Synthesis of Five-Membered Heterocylic Derivatives (1, 3, 4-oxadizoles) by Using Grinding Technique
by: Nihad Taha, et al.
Published: (2018-09-01)