Biomimetic nanocarriers loaded with temozolomide by cloaking brain-targeting peptides for targeting drug delivery system to promote anticancer effects in glioblastoma cells

Biomimetic nanocarriers loaded with temozolomide by cloaking brain-targeting peptides for targeting drug delivery system to promote anticancer effects in glioblastoma cells

Glioma is the leading cancer of the central nervous system (CNS). The efficacy of glioma treatment is significantly hindered by the presence of the blood-brain barrier (BBB) and blood-brain tumour barrier (BBTB), which prevent most drugs from entering the brain and tumours. Hence, we established a n...

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Bibliographic Details
Main Authors: Huaming Chen, Yunhong Wang, Hai Wang, Kun Zhang, Yunfei Liu, Qiangfeng Li, Chengli Li, Zhonghui Wen, Ziyu Chen
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Heliyon
Subjects:
Apoptosis
Blood-brain barrier
Glioblastoma
Temozolomide
Zein
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024042877

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